Brain catecholamines and blood flow.
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Animals↗
Biomedical subjects
M Lavyne
Publications and source records attributed to M Lavyne.
Rotational behavior in gerbils following unilateral common carotid artery ligation.
Unilateral cerebral infarctions are produced in 30-50% of all gerbils subjected to ipsilateral ligation of a common carotid artery. It has previously been shown that this infarction is associated with a major depletion if ipsilateral brain dopamine. The present studies characterize the spontaneous and drug-induced rotational behavior manifested by these animals and attempt to relate it to the functional activity of dopaminergic synapses. The tendency of animals to turn towards the side of the lesion 2-3 hours after surgery was found to correlate highly with the unilateral dopamine depletion observed after 24 hours. Two patterns of rotational responses were observed among animals showing symptoms that were treated with d-amphetamine or apomorphine; these could be correlated with mortality 24 hours after surgery.
Amphetamine↗
Sarcoidosis presenting as cervical radiculopathy: a case report and literature review.
A unique case of sarcoidosis, presenting as a unilateral multilevel cervical radiculopathy without spinal cord compression, is discussed. The clinical presentation, along with the initial myelographic findings and emphasis on local compressive etiologies delayed the diagnosis. The aim of this report is to focus on this unique entity and to review its role in the differential diagnosis of patients with atypical cervical radiculopathy. A pleocytosis of cerebrospinal fluid, an increase in protein concentration, and hypoglycorrhachia support the diagnosis of spinal cord sarcoidosis. While the outlook for patients with spinal cord sarcoid is poor, improvement of neurologic deficits has been documented after steroid therapy. A review of the literature on sarcoid involvement of the spinal cord and roots is summarized.
Adult↗