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Biomedical subjects

M Lazović

Publications and source records attributed to M Lazović.

7 recordsLinked to original sources
PubMed1993

[Skin changes in patients with Lyme borreliosis].

In introduction some clinical characteristics of Erythema migrans, Borrelia lymphocytoma and acrodermatitis chronica atrophica has been described. The importance of atypical forms of Erythema migrans and the difficulties in differential diagnosis of cutaneous manifestation has been stressed. In a prospective, and partly retrospective investigation of 1292 persons with tick bites, signs of Lyme borreliosis have been found in 18.96%. Number of such persons seen in dermatology wards is rising, and 18.2% of these are children less than 15 years of age. Patients seen in dermatology are mostly women (56.5%:43.5%). Nearly half of the patients with Erythema migrans did not known that they had a tick bite (42.5%). Lyme borreliosis was manifested mainly as Erythema migrans, 89% of patients. Borrelia lymphocytoma was encountered in 2%, and Acrodermatitis chronica atrophicans in 0.4% of patients, significantly less than in other reports. Sclerotic skin lesions were found in 4.1% of patients, and some macular and urticarial lesions were recorded. An incubation period generally less than three weeks preceded to skin manifestations, but in some patients this period could not be recorded. Skin lesions were located on lower extremities in 50.4% of patients, trunk in 25.5%, and upper extremities in 10.5% of patients. In 87% of patients skin lesions lasted less than three weeks. Symptoms were present in 62% of patients. Seropositivity to Borrelia burgdorferi has been found in 10.2% of patients, mostly three weeks after the tick bite.

Adolescent↗
PubMed1993

[Cutaneous manifestations of Lyme disease and results of our study].

An investigation of 395 patients with tick bites or suspected tick bites has been conducted. Patients were from 14 months to 86 years old. Erythema migrans was found in 83 (21.01%), lympocytoma in 2 (0.5%) and scleroderma lesions in 2 (0.5%) patients. There were 12 asymptomatic seropositive patients. The presence of Borrelia burgdorferi in two Ixodes ricinus ticks was investigated and demonstrated.

Adolescent↗
PubMed1993

[Lyme disease in children and adolescents].

148 children and adolescents with Lyme borreliosis and tick bite or suspection on tick bite were examined. The examined patients were aged from 14 months to 24 years and divided into four age groups. Skin lesions were discovered in 25 percent of patients with tick bite. Erythema migrans occurred in 91 percent, Lymphocytoma in 3 percent and sclerodermatous lesions (Lichen sclerosus et atrophicus and Morphea) in 6 percent of patients with Lyme disease. Serologic tests on the presence of antibodies to Borreliae burgdorferi were performed in 96 percent of cases with tick bite. Antibody titer 1:80 or higher in 8 percent of patients with tick bite, was discovered. We found positive serologic test results in 5 (29 percent) of 29 persons with Erythema migrans, in 4 (4 percent) of 110 patients with tick bite (without skin lesions), as well as, in 1 patient with Lymphocytoma. Antibiotic therapy was applied in all cases with Erythema migrans, in person with Lymphocytoma, as well as, in patients with asymptomatic infections (patients without skin lesion recalling a tick bite and with antibodies against Borrelia burgdorferi). A general sensitivity, to infection with Borrelia burgdorferi, is stressed, a fact based on appearance by Lyme borreliosis in all age groups even in the newborn children.

Adolescent↗
PubMed1993

[Epidemiologic characteristics and serologic findings in erythema migrans].

Our three-year research covered 417 patients with erythema migrans, of both sexes and all age groups. Among them 87.3% had a history of tick bite. Average attachment of tick to a patients skin was two days. Diameter of erythematous lesions was 1-50 cm (with an average of 15.1 cm). Magnitude of the lesion does not correlate with the further development of the Lyme disease. IFA test detected antibodies against Borreliae burgdorferi in 27.0% of our patients.

Adult↗
PubMed1989

[Use of external fixators in infected fractures].

The purpose of this study was to present our own experience with external fixation in the treatment of infected fractures. External fixation was first used in the Trauma Center of Sarajevo in 1972 for the treatment of infected concquassant fracture of the lower leg. Since then it has been used in 111 patients. In most of the cases we have used AO fixation, the Hoffmann external fixation, and, more recently, the Ilizarov device. External fixation was applied in 49 cases with the infected fractures out of the total number of 111. Forty six of the patients were males and the fractures involved 31 lower legs, 13 upper legs, 3 forearms, and 2 upper arms. The work presents our own experience concerning etiology, a type of injuries, method of choice, length of the treatment, complications and results.

Adult↗