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Biomedical subjects

M Leach

Publications and source records attributed to M Leach.

66 records · Page 4Linked to original sources
PubMedDate not supplied

A new variant of blood group A. Apae.

A new variant of blood group A, termed Apae, was found as an inherited characteristic in three unrelated white families. Apae was distinguished from other A variants by its agglutination and absorption-elution reactions with only certain human anti-A and -A,B serums, by the red cells that reacted with anti-A from Helix pomatia without the need for enzyme treatment, by enhancement of the latter reaction with bromelinization, and by the presence in the serum of an anti-A of normal avidity and titer. Apae also reacted strongly with a recently discovered anti-A agglutinin derived from the seaweed Codium fragile, subspecies atlanticum, but not with a series of other anti-A lectins. It was concluded that Apae cells express only part of the normal A antigen and that the anti-A present in the serum does not have an anti-Apae component.

ABO Blood-Group System↗
PubMedDate not supplied

Juvenile chronic arthritis: epidemiology and genetics.

This article looks at the classification, epidemiology and possible causes of juvenile chronic arthritis. The clinical manifestations of the different types of this disease are discussed. Finally the course and prognosis of this disease are described. A second article on juvenile chronic arthritis will appear on May 28 1997.

Arthritis, Juvenile↗
PubMedDate not supplied

The social effects of juvenile chronic arthritis.

We are continually expanding our knowledge of JCA and establishing our understanding on an ever-increasing knowledge base encompassing immunology, immunogenetics, physiology, psychology and sociology. The causes and treatment of this condition are multifactoral and no one discipline can hope to embrace all of them. Nurses, particularly those with rheumatological and/or paediatric expertise, are uniquely placed to provide the link between patient, the family and health care team and thus to coordinate treatment and ensure that care meets the needs of youngsters with JCA and their families.

Adolescent↗