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Biomedical subjects

M Lecompte

Publications and source records attributed to M Lecompte.

6 recordsLinked to original sources
PubMed2000

Fluorine-18 fluorodeoxyglucose positron emission tomography correlated with computed tomographic scan and magnetic resonance imaging in a case of hematometrocolpos.

A 12-year-old girl had intense abdominal pain that had increased in the past 3 months and was accompanied by weight loss. An ultrasound examination revealed large cystic masses in the abdomen. A computed tomographic scan could not conclusively rule out a malignant condition. The hymen was normal on physical examination, but magnetic resonance imaging confirmed that the abnormalities corresponded to dilated cavities of the vagina, uterus, and fallopian tubes, with an appearance suggestive of hematometrocolpos. Fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography was requested concurrently with the magnetic resonance image to assess the metabolic activity of the lesions and to exclude the presence of distant metastases. Large defects without FDG accumulation were noted in the areas corresponding to the cystic masses. Vaginal atresia with hematometrocolpos was confirmed at surgery. This rare case involving F-18 FDG positron emission tomographic imaging in hematometrocolpos illustrates that this diagnosis should be considered in the presence of symmetric hypometabolic masses in the pelvis.

Child↗
PubMed1998

Schnitzler's syndrome.

We report on a case of Schnitzler's syndrome, focusing on pattern of bone involvement and its differential diagnosis.

Aged↗
PubMed1994

[A retrospective study of 93 cases of orbital and eye tumors using tomodensitometry].

The purpose of this study was to review certain computed tomography (CT) criteria in relation to the histopathologic diagnosis of orbital tumours. One hundred and forty cases of orbital tumour were evaluated by CT between 1979 and 1992 at two tertiary-care hospitals. The radiologic material was available and the histopathologic diagnosis had been clearly established for only 93 of these; these cases were reviewed in detail for the study. The radiologic semiology of the cases was compared with the pathological diagnosis. The characteristics evaluated were tumour localization, attenuation, contrast enhancement, the presence of calcifications, the morphologic features and changes in the neighbouring bony structures. The authors present here the findings for the most commonly encountered tumours: uveal melanoma (observed in 50 cases), lymphoma (in 8), optic glioma (in 6), meningioma (in 6), dermoid cyst (in 5) and metastasis (in 5). Using the current literature for corroboration, the authors suggest an approach to diagnosis on the basis of the CT criteria discussed.

Adolescent↗
PubMed1988

Energy balance and facultative diet-induced thermogenesis in mice fed a high-fat diet.

The present study was aimed at studying energy balance in mice fed a high-fat diet. Albino mice were divided into three groups. One group had free access to the stock diet, whereas the two other groups consumed a high-fat diet. One of the high-fat fed groups was fed ad libitum, whereas the other was offered a restricted amount of the same diet so that its energy intake was comparable to the group of mice given the stock diet. Energy balance measurements, which included indirect calorimetry and carcass analysis, were performed. Brown adipose tissue (BAT) properties were also investigated. The results show that gains in both body weight and fat were higher in mice that had free access to high-fat diet than in mice fed the stock diet. In animals given a restricted amount of the high-fat diet, fat gain increased, whereas protein gain was reduced in comparison with animals fed the stock diet. Unrestricted access to the high-fat diet led to an increase in both energy intake and energy gain. As revealed by both slaughter and indirect calorimetry techniques energy expenditure was, in high-fat fed mice, 40% higher than in animals fed either stock or a restricted amount of high-fat diet. Nadolol was shown to suppress a large part of the elevated metabolic rate seen in mice fed an unrestricted high-fat diet. In those mice, BAT mitochondrial GDP binding was also increased. In summary, the present results confirm that adaptive diet-induced thermogenesis (DIT) develops in mice made hyperphagic by an energy-dense palatable diet.(ABSTRACT TRUNCATED AT 250 WORDS)

Adipose Tissue, Brown↗