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Biomedical subjects

M Lefèvre

Publications and source records attributed to M Lefèvre.

54 records · Page 3Linked to original sources

[Multinodular hepatic angioma: a rare cause of neonatal asystole. A case and review of the literature].

The clinical findings in a case with a diffuse multinodular type of angioma of the liver are reported. The clinical picture was typical: the appearance after the first week of a severe congestive failure mimicking a congenital heart disorder, of the left to right shunt type, with gross hepatomegaly of the "vascular" type with a systolo-diastolic murmur, but with no cutaneous evidence of angioma. The very severe prognosis during the first months of life of patients with this malformation, as illustrated by the 58 deaths out of the 78 cases reported in the literature, indicated ligature of the hepatic artery before the age of one month. The satisfactory outcome (with a nine months follow-up) for this case, as for the three other operated cases in the literature, leads us to conclude that this operation is indicated after a detailed arteriographic examination has been made, and provided that the other anatomical conditions are favourable.

Arrhythmias, Cardiac↗

rRNA gene restriction patterns of Legionella species: a molecular identification system.

A total of 28 species of Legionella could be differentiated by rRNA gene restriction patterns generated after cleavage of total DNA with either EcoRV or HindIII restriction endonucleases, and hybridization of fragments with 32P-labelled Escherichia coli 16 + 23S rRNA. Different species gave different fragment patterns. When several isolates of a species were tested, the patterns obtained were often identical. However, more than one pattern was often observed when more than one serotype was considered. The method should be useful for the identification of all species of Legionella including those exhibiting immunological cross-reactions.

DNA Restriction Enzymes↗

Persisting spongy myocardium. A case indicating the difficulty of antenatal diagnosis.

Persisting spongy myocardium (also known as noncompaction of the ventricular myocardium) is a rare and special form of cardiomyopathy. The few cases reported in the literature were detected postnatally and involved a high rate of cardiovascular complications. This anomaly of endomyocardial morphogenesis, which occurs during the embryonic phase at the stage of cardiac partitioning, is characterised by an excessive number of prominent trabeculae and by intertrabecular recesses within the myocardial wall. Antenatal detection is difficult in the absence of an associated malformation, which is the general situation. We report a case of antenatal cardiomyopathy which led to therapeutic abortion. The diagnosis of persisting spongy myocardium was made during fetopathologic examination.

Abortion, Therapeutic↗

[15 new serotypes of Salmonella of subgenus I isolated in Africa].

Filteen new serotypes of Salmonella belonging to the sub-genus I have been isolated in Africa. Isolated in Ivory Coast: S. dabou (8,20:Z4,Z23,l,W), S. elokate (9,12:c:1,7), S. assinie (3,10:1,w:Z5), S. anna (13,23:Z35:e,n,Z16), S. mpouto (16:m,t:-), S. banco (28:r:1,7), S. abidjan (38:b:l,w); in Senegal: S. bignona (17:b:e,n,Z15), S. lode (17:r:1,2), S. derkle (52,e,h:1,7); in Tchad: S. moussoro (1,6,14,25:i:e,n,Z15), S. drogana (1,4,12,27:r,i:e,n,Z15); in Algeria: S. hydra (21:c:1,6); in Haute-Volta S. farakan (28:Z10:1,5); in Republique Centrafricaine: S. babili (28:Z35:1,7).

Adult↗