[Prenatal protection. Regulation. Perinatal mortality. Epidemiology].
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Biomedical subjects
Publications and source records attributed to M Leloup.
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In France, 8% of the population are foreign. They come from the lowest socio-economic level. In distinguishing the new arrivals from those who have lived in France for several years, the migrant related health patterns are applied. Health problems of foreigners in France can be examined in a number of different ways: --Foreign workers are found in unskilled work and in jobs where they are constantly subjected to hazards of the workplace, occupational health risks and accidents. --The quality of maternal and child health care among foreign women is lower than among the French. --Foreign children are hospitalized more often and for longer than French children. The types of illness are not specific. The truancy rate is more significant than the national mean. --Restrictions on the opportunities for enjoying certain social rights, administrative and financial obstacles encountered as well as difficulties in communication all make it harder to meet the needs of this section of the population.
The tendency of subjects to maintain their relative position within the distribution of blood pressure (BP) has been defined as "tracking". Regarding this phenomenon, the purpose of the study was to evaluate the interest of ambulatory BP monitoring (ABPM) in the assessment of arterial hypertension in young adults (YA) with childhood hypertension history (CHH). 52 subjects, 20.1 +/- 2.4 years old, 26 men, 26 women issued from a cohort of 150 children with high BP levels (greater than 97.5 th percentile) during their infancy (school check-up), were included in the study. An ABPM was performed with space-labs system 90202 from 8 a.m. to 6 p.m., measurements every 15 minutes (37.6 +/- 7.4 readings). Left ventricular mass index (LVMI) was determined with echocardiography, (Penn convention). Office BP, measured with mercury apparatus in lying and standing position, was respectively, 131.0 +/- 14.6/81.9 +/- 9.7 and 130.1 +/- 14/86.6 +/- 9.9. According to JNC 1988, this casual BP identified 40 normotensives (NT), 9 borderlines (BL) and 5 hypertensives (HT); 10 of them had a "high normal" diastolic BP (85-90 mmHg) ABP recordings of the study group were compared to day-time reference values of NT. Three subgroups are individualized: G1 NT, G2 HT, G3 BL. [table; see text] *p: less than 0.001; p: less than 0.01. Wall thickness (WTh) and LVMI were significantly higher in hypertensives (G2 + G3) than in normotensives (G1): [table; see text] There was a significant correlation between LVMI and mean systolic ABP (p less than 0.01: r = 0.44), but not with office SBP.(ABSTRACT TRUNCATED AT 250 WORDS)
In order to get a better knowledge on respiratory illnesses of children in Toulouse, and to evaluate the influence of air pollution, 1,000 children between 8 and 11 years of age, living in five different areas of the city were observed during one year (March 1985-March 1986), together with the measure of twenty pollutants. A questionnaire was used to assess the history of respiratory diseases and the chronic respiratory pathology. According to the areas, no difference appeared, other than the frequent cough which is more important in an area with lower social income (p less than 0.01). The acute respiratory illnesses, as noted during the year of observation, had a different pattern according to the areas (p less than 0.0001). Amongst the five pollutants used for the analytic study through the cross-correlations, four: nitrogen monoxide and dioxide, black fumes, and ammonia particulate derivatives are related to the respiratory diseases.
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A 17-month old boy is partially trisomic for 7q22 and 7q31 due to a probable insertion in the paternal chromosome 13. The phenotype of the patient is similar to that of two other patients reported in the literature.
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The GRES 31 is a small study group which was established in 1982 in Toulouse, France. Its aims are to promote health among underprivileged groups such as gypsies, immigrants from North Africa... in the local communities. The local community is envisaged as an area where the social structure which has become pathogenic (bad work conditions, destruction of human links...) can be reshaped for a healthy life. The approach of GRES 31 is "global": the health problems of an individual cannot be separated from the overall life context of his group. The ethnic culture and collective behaviour of the group is closely related to the demand for care and the health outcome. On such a pre-requisite, the social scientist has to play his role together with the health professionals. The term of "research" (i.e. "social research") is to be supplemented by that of "experiment". Moreover, health promotion cannot merely imply guidance from the outside but primarily participation from inside the local communities. Such an approach is not a novelty: as a matter of fact, the works of the French hygienists in the 19th century paved the way for a pluri-disciplinary perspective in health work. In some circumstances, the "researchers-experimenters" cannot avoid certain conflicts among themselves: for example when an ill child is endangered by the observance of the ethnic traditions of his own group. More generally, efforts to reduce "clinical imperialism", "State interventionism", "local bureaucracy"... could be of light weight when dealing with "macro-problems" such as nuclear risk, AIDS, or health cost containment.