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Biomedical subjects

M Lerner

Publications and source records attributed to M Lerner.

At least 55 records · Page 3Linked to original sources
PubMed1989

Effect on airway resistance of ketamine by aerosol in guinea pigs.

The effect of aerosolized ketamine hydrochloride was investigated by measuring airway resistance with a two-compartment plethysmograph in guinea pigs challenged with histamine. In the first phase of the study, treatment with ketamine prior to histamine challenge did not protect against elevation of airway resistance. In the second phase of the study, ketamine inhalation after histamine challenge did not significantly diminish airway resistance. Aerosolized ketamine is not recommended for use in human subjects with asthma.

Aerosols↗
PubMed1987

Stimulation of murine cultured mast cells under anaerobic conditions: inhibition of arachidonic acid release.

The exocytosis of beta-hexosaminidase from either IgE-antigen- or calcium ionophore A23187-stimulated murine bone-marrow-derived mast cells was not affected by oxygen-depleted conditions regardless of the absence of glucose from the medium. No detectable changes in the content of ATP were observed when the cells were triggered immunologically under anaerobic conditions in the absence of glucose in the medium. Depletion of oxygen from mast cells activated by both stimuli almost completely inhibited the specific release of arachidonic acid, which indicates that arachidonate does not play a significant role in the secretion of preformed mediators.

Adenosine Triphosphate↗
PubMed1986

Common origin of inferior mesenteric and main renal artery.

The first case of a common origin of both the inferior mesenteric and single main renal artery, angiographically documented in a patient with primary ipsilateral ectopic kidney, is reported. Embryologic as well as surgical aspects are mentioned.

Aortography↗
PubMed1984

Site of entry of single main renal artery. Angiographic study.

In an effort to determine the frequency of extrahilar entry of the single main renal artery, renal angiographies of 124 left and 124 right kidneys were examined and the findings reviewed. Extrahilar entry of the main renal artery was found in 33 per cent of the kidneys. In 81.7 per cent of the kidneys with extrahilar entry, the artery penetrated the kidney through the upper zones (above the normal hilus). Apical entry of the renal artery was found in 1.6 per cent of the 248 kidneys. There was no entry of the single main renal artery below the hilus of the right kidney. An embryologic explanation of these findings is suggested, and some practical aspects are mentioned.

Adolescent↗
PubMed1983

Apical entry of single main renal artery.

Two cases of extrahilar entry of a single main renal artery are described. Selective renal angiography demonstrated arterial entry through the upper pole of the kidney and venous exit, adjacent to the arterial entry. Embryologic as well as some surgical aspects are presented. To our knowledge only one similar variation of arterial supply to the kidney has been reported previously.

Aged↗
PubMed1983

The decline in the Blue Cross Plan admission rate: four explanations.

Between 1968 and 1979, there occurred a steady decrease in the hospital admission rate for Blue Cross Plan members, in contrast to the steady increase in the admission rate for the under-65 U.S. population as a whole. Four general factors were studied to explore the reasons for this relative decrease: utilization control and cost containment activities instituted by Blue Cross Plans, the decline in Plan nongroup membership, duplicate coverage within families, and deficiencies in the family factor technique to estimate overall Plan membership. With some interesting exceptions within one of the factors, all four offer plausible explanations for the decline in the admission rate among Blue Cross Plan members.

Blue Cross Blue Shield Insurance Plans↗
PubMed1981

An analysis of observed attention and activity patterns in preschool children.

An activity-attention scale was incorporated into the Pediatric Examination of Educational Readiness to determine whether performance of age-appropriate tasks would elicit or provoke attentional weakness or activity level modulation in a sample of prekindergarten children. Thirty-three (9.8%) of the 338 children met the criteria of weak attention and/or increased activity at one time during the assessment, and 18 (5.3%) met the criteria at two or more times. The "flagged" children were more likely to be boys and to have other developmental findings, lower McCarthy scores, and teacher concerns. Significant fluctuation of attention was noted commonly during the sessions. Furthermore, difficulty in interrater scoring of severity was demonstrated. This study underscores the variability and complexity of attention and activity findings, and confirms the need for direct observation as well as integration of information from all available sources.

Attention↗
PubMed1981

The single drug user and his audience.

Observations on youth life in a slum of Tel-Aviv revealed a situation in which one youngster smokes hashish while he is surrounded by his nonuser friends. Symbols of reliance on friends are the essence of this interaction. The situation denies a group pressure on this drug user. The individual's needs in social bonds, expressed in the interaction, suggests a direction for an intervention program focused on the drugged personal needs.

Adolescent↗
PubMed1975

Impact of membership in an enrolled, prepaid population on utilization of health services in a group practice.

Members of prepaid group-practice medical-care plans are believed to use more ambulatory, but fewer inpatient, services than populations served by fee-for-service practitioners. It is not known whether these differences are attributable to the prepayment aspects of the plan or to other circumstances. We studied the impact on use of services of only one factor-prepayment at the Marshfield Clinic, Wisconsin--with all other factors, including group practice, held constant. The findings were derived from the experience one year before, and two years after, the initiation of the prepaid program. Results showed that prepayment alone resulted in significant increases in both inpatient and ambulatory care (about 100 per cent in ambulatory-care visits, 75 per cent in hospital discharges, and 60 per cent in hospital days). These increases were far greater than comparable increases in the fee-for-service population served by the Clinic.

Ambulatory Care↗