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Biomedical subjects

M Liance

Publications and source records attributed to M Liance.

42 records · Page 3Linked to original sources

Acquired immunodeficiency with intestinal cryptosporidiosis: possible transmission by Haitian whole blood.

A 31-year-old Frenchman had an acquired immunodeficiency syndrome (AIDS) with profound depression of cellular immunity and relative sparing of humoral immunity. The clinical picture included intractable secretory diarrhoea, vomiting, abdominal pain, and weight loss. Gastrointestinal cryptosporidiosis was present and a perfusion technique showed profuse secretion of fluid in the proximal small bowel. The patient also had recurrent Salmonella typhimurium septicaemia, cytomegalovirus infection, and cerebral toxoplasmosis and he died within 13 months. This patient did not belong to any of the groups known to be affected by this type of acquired immunodeficiency (homosexuals, drug addicts, haemophiliacs, Haitians) but had been transfused with Haitian blood 4 years before onset of symptoms. This case supports the notion that some forms of AIDS may be transmitted by blood, with a long incubation period.

Acquired Immunodeficiency Syndrome↗

[Arvicola terrestris (L.), the first rodent found naturally infested with Echinosoccus multilocularis, Leuckart, 1863, in France].

One of 400 A. terrestris trapped in the east of France (Jura and Alpes), contained a hepatic hydatid characteristic of the species E. multilocularis. 1 296 other Rodents, belonging to 11 species had been previously screened unsuccessfully. This positive result and the close resemblance between the distribution of the human cases of the disease and the areas of maximum proliferation of A. terrestris suggests that this species can play an important role in the persistence and geographic localisation of the zoonose.

Animals↗

[Comparative values of homologous and heterologous antigens in the diagnosis of hydatidosis and alveolar echinococcosis using immunofluorescence].

Scoleces of E. multilocularis obtained from experimentally infested animals are compared with scoleces of E. granulosus from naturally infested animals towards homologous and heterologous sera (fluorescent antibody test). The antigens of larvae of both species are differently located, but larvae show a very close degree of antigenic reactivity. The use of scoleces of E. multilocularis does not improve the sensibility of the test applied to the diagnosis of echinococcosis. But the production of large amounts of antigen might allow regular investigations among high risk people.

Antigens↗