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Biomedical subjects

M Liern

Publications and source records attributed to M Liern.

11 recordsLinked to original sources
PubMed2004

[The additive antiproteinuric effect of Enalapril and Losartan to normotensive patients with pathology proteinuria].

UNLABELLED: The proteinuria is frequently the initial insult to the kidney and it usually followed by a progressive decline in the glomerular filtration rate. The angiotensin II mediate by glomerular permeselective function via the opening of large pores after elevations in transmembrane pressure and by acting on the glomerular pressure, too. There is evidence that angiotensin-converting enzyme inhibitors alone or with the angiotensin receptor-blockade may improve the glomerular size-selective function and the hemodynamic intrarenal accounted output of plasma proteins. We evaluated the Enalapril action only in two progressive doses (stage 1: 0.2 mg/kg/day and stage 2: 0.4 mg/kg/per day, respectively) and then we evaluated the combinated treatment (stage 3) with Enalapril (0.2 mg/kg/per day) + Losartan (0.8 mg/kg/day) in thirteen patients (2 female/ 11 male, mean age 12 yrs, r: 10y-16y) normotensive with middle or heavy proteinuria and normal glomerular filtration rate. The study lasted six months. In the three stages occurred decrease of the urinary protein, but only the stage 2 and 3 was significant (p < 0.05). And the three stages had significant reduction of the mean blood pressure, too (p < 0.05). On the other hand there has a good correlation between the less proteinuria and the descent of the mean blood pressure in the stage I (r: 0.75, p < 0.05) and the stage 2 (r: 0.70, p < 0.05), but this did not occur in the stage 3 (r: 0.37, p < 0.1). No patient had raise serum potassium; neither did they have decrease glomerular filtration rate or anaemia. CONCLUSION: The coadministration of Enalapril and Losartan was the most efficient treatment antiproteinuric effect. It was not only by the drug related reduction in systemic blood pressure. There weren't any adverse side effects in any patient dependent of the medication.

Adolescent↗
PubMedDate not supplied

[Presentation of Burkitt's lymphoma in nasal sinus].

Burkitt' lymphoma is a malignant, non-Hodgkin's lymphoma of high grade that present two clinical from the african or endemic form affects near the middle of children of central africa and the american or sporadic form, that was first described in North American and the clinical setting was similar to endemic form. In our geographic area is an unusual entity. We present a clinical case of marrocan child that the first symptom was nasosinusal.

Adolescent↗
PubMedDate not supplied

[Nasosinusal inverted papilloma].

Inverted papilloma is a papillar lesion of the nasal cavity and paranasal sinuses that arise from the Schneiderian membrane. This tumor has a high rate of local recurrence. We present a review of 10 cases of inverted papilloma of the nose and paranasal sinuses. A review of the literature is done.

Adult↗
PubMedDate not supplied

[Unusual manifestations of squamous carcinoma of the lip].

We present a case of squamous cell carcinoma of the lip with metástasis to the mandible and meningeal involvement causing multiple cranial nerve palsies. Biopsy proven metástasis to the mandible was demonstrated. Studies of CT scan of the head were negative. Extension through perineural space have been speculated.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

[Review of 156 myringoplasties].

We report the anatomical and functional results of 156 myringoplasty; 134 with onlay surgical technique and 22 with underlay technique. We comment the climatologic of our area and its relation with the surgical failures.

Adolescent↗
PubMedDate not supplied

[Cranioencephalic traumatism. Audiovestibular sequelae].

A group of 80 patients with blunt head injury were examined. Long-term clinical neurologic and otologic sequelae of traumatic head injury are well recognized. The authors studied the vestibular disorders using ENG, EEG and high resolution CT.

Adolescent↗
PubMedDate not supplied

[Primary malignant melanoma of the nasal cavity].

This refers to a case of a malign melanoma in the nasal cavity. Melanomas of the mucosal origin differed from the melanomas cutaneous in that size of the primary lesion did not influence prognosis. Regional lymph node metastases are rare and did not influence prognosis. Local recurrence at the primary site is frequent. Surgical treatment offers long-term cure to only a limited number of patients.

Female↗