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Biomedical subjects

M Liew

Publications and source records attributed to M Liew.

8 recordsLinked to original sources

Predictability of excimer laser treatment of myopia and astigmatism by the VISX Twenty-Twenty. Melbourne Excimer Laser Group.

BACKGROUND: To determine the predictability of excimer laser photorefractive keratectomy (PRK) to correct myopia, astigmatism, or both between -1.00 and -19.00 diopters (D). SETTING: Royal Victorian Eye and Ear Hospital, East Melbourne, Australia. METHODS: This study comprised 1218 consecutive eyes treated with a VISX Twenty-Twenty excimer laser and followed prospectively for 12 months. Low myopia was treated with one ablation zone (6.0 mm), high myopia with two ablation zones (5.0 and 6.0 mm), and extreme myopia with three ablation zones (4.5, 5.0, and 6.0 mm). Maximum spherical treatment was 15.00 D at the corneal plane. Data were analyzed to determine the predictability of the postoperative outcomes by preoperative refraction. RESULTS: Nine hundred eighty eyes (80.5%) were available for the 12 month follow-up. The predictability of refraction and uncorrected and best corrected visual acuities progressively decreased with increasing myopia, although a comparable percentage of spherical correction was achieved at each diopter of myopia. The likelihood of losing lines of best corrected visual acuity and corneal haze increased with increasing myopia. CONCLUSION: These data can be used to counsel patients of likely outcomes of excimer laser PRK to correct myopia.

Adult↗

Ergonomic education for nursing students.

An educational package of common ergonomic training as well as behavioural training was implemented in nursing education. The teaching methods also had the aim of increasing students' awareness of the importance of total work environment for the prevention of back injuries. The experimental group was, on the whole, more pleased with their education than the control group. The experimental group judged their ability to analyse the work environment higher than the control group did. Observations in some practical work-tasks showed that students from the experimental group worked in physically more favourable positions with less strain on the body.

Curriculum↗

Clinical significance of immune complexes in rheumatoid disease.

Circulating immune complexes were measured by the Clq binding assay in 49 cases of rheumatoid disease. Raised levels showed a positive correlation with activity of the arthritis, the number of involved joints and the erythrocyte sedimentation rate. No correlation was found with age, sex, duration of disease, rheumatoid nodules, presented of radiographic joint erosions or other haematological and serological parameters. In 12 patients the arthritis subsequently remitted and this remission in disease activity correlated with reduced levels of immune complexes.

Antigen-Antibody Complex↗

Three multizone photorefractive keratectomy algorithms for myopia. The Melbourne Excimer Laser Group.

OBJECTIVE: To compare the efficacy and complications of three different excimer laser algorithms for multizone photorefractive and photoastigmatic keratectomy. METHODS: Three different software algorithms were applied to treat myopia and myopic astigmatism with the VISX 20/20 excimer laser. Each algorithm had a maximum ablation zone of 6 mm but differed in the number of zones employed, the proportion of the total treatment allocated to each ablation zone, and the treatment of astigmatism. The Melbourne multizone technique equally divided myopia correction into a maximum of three ablation zones. The Pop multizone technique biased myopia treatment into the smaller diameter zones to a maximum of six ablation zones, with one central island pretreatment. The Alpins multizone technique equally divided myopia treatment through all zones up to a maximum of six, with one central island pretreatment. RESULTS: A total of 585 patients (780 eyes) were treated and 625 eyes (80%) were followed for more than 6 months. The mean baseline spherical equivalent refractive error was -5.63 D (-1.00 to -19.50 D). Between 71 and 79% of eyes were treated for astigmatism. There was no statistically significant differences in baseline refractive error or other characteristics among the three groups. At 6 months, the Alpins multizone algorithm had more eyes with a refractive error within +/- 1.00 D of emmetropia (p = 0.01) and more within +/- 2.00 D of emmetropia (p < 0.01). This new algorithm produced more eyes with an uncorrected visual acuity of 20/20 or better at 6 months (p < 0.01). When multiple logistic regression was used to correct for any differences in baseline myopia among the three groups, this algorithm also had a higher odds ratio for achieving 20/20 or better uncorrected visual acuity (OR = 1.58). CONCLUSION: At 6 months, all three algorithms were effective in the reduction of myopia. Significantly better visual acuity and refractive results were achieved with the Alpins multizone algorithm that spread the total treatment over a larger number of ablation zones, with an equal number of diopters of treatment in each zone.

Adolescent↗