Biomedical subjects

M Lipshits

Publications and source records attributed to M Lipshits.

16 recordsLinked to original sources

PubMed1999

Gravity affects the preferred vertical and horizontal in visual perception of orientation.

The aim of this study was to evaluate the influence of gravity on the representation and storage of visual orientation information. On earth, measurements of response time and variability for a task of aligning remembered visual stimuli showed a distinct preference for horizontally and vertically oriented stimuli when the body and gravitational axes were aligned. This preference was markedly decreased or disappeared when the body axis was tilted with respect to gravity but was maintained for tests performed in microgravity. We conclude that subjects acquire and store visual orientation in a multi-modal reference frame that combines proprioceptive and gravitational information when both are available.

Adult↗

PubMed1998

Temporal control and motor control: two functional modules which may be influenced differently under microgravity.

Three subjects performed sequences of periodic movements by synchronizing their movements (button pressing with the thumb) to a series of visual stimuli (induction phase), and by continuing to produce the movements with the same rhythm after the metronome had been switched off (continuation phase). The required inter-response intervals (IRIs) were 450, 550 or 650 ms. Two subjects were members of the EUROMIR 94 spaceflight mission. The inter-response intervals of the continuation phase were analyzed in terms of mean and variability. The mean inter-response intervals did not differ systematically during spaceflight from the pre- and post-flight values. The variability of the inter-response intervals significantly increased during the flight with both experimental subjects. The total variance of the inter-response intervals was partitioned into variance due to the internal timekeeper and variance due to the motor implementation processes, following the method proposed by Wing, A.M., Kristofferson, A.B., 1973. Response delays in the timing of discrete motor responses. Perception and Psychophysics 14, 5-12. The variance attributed to the timekeeper showed a significant increase with both subjects, whereas the variance attributed to the motor processes showed inconsistent trends during the spaceflight. It is concluded that during spaceflight, the functioning of the internal timing module may undergo some changes, as the result of which the regularity of the motor timing is slightly impaired.

Adult↗

PubMed1995

Is there an effect of weightlessness on mental rotation of three-dimensional objects?

We studied the performance of eight cosmonauts in a mental rotation paradigm with simultaneously presented perspective views of three-dimensional objects. The cosmonauts were tested successively on earth, in microgravity aboard the Russian MIR station and again on earth. Their performance was compared to performance of a control group of five subjects tested on earth on the same dates. We particularly tried to disambiguate the effect of microgravity, procedural bias and practice. Our results show that the microgravity did not alter the mental rotation process. The performance of cosmonauts increased with practice, similarly to the performance of control group's subjects suggesting that the weightlessness did not impair implicit learning as well. Finally, we propose an explanation of previous contradictory results.

Adult↗

PubMed1995

Independence of bilateral symmetry detection from a gravitational reference frame.

Data were collected during three orbital flights aboard the Russian MIR space station from eight cosmonauts tested on a bilateral symmetry detection task. It is known that on earth subjects' performance is significantly superior for a vertical or horizontal than for an obliquely oriented axis of symmetry, giving a so-called oblique effect. The present results show that this oblique effect did not disappear in microgravity. They confirm that the detection of visual symmetry is not tied to a gravitational reference frame. An unexpected result of the experiments was that practice reduced the reaction time for detection of asymmetrical patterns below that for symmetrical patterns. This result suggests the presence of two separate detection processes. The detection of symmetry, being useful for the efficient encoding of visual information, is well developed in naive subjects. Extensive practice on a symmetry-detection task, however, increases the efficacy of the asymmetry-detection process.

Adult↗

PubMed1993

Effects of prolonged weightlessness on mental rotation of three-dimensional objects.

Previous experiments have suggested that the analysis of visual images could be a gravity-dependent process. We investigated this hypothesis using a mental rotation paradigm with pictures of three-dimensional objects during a 26-day orbital flight aboard the Soviet MIR station. The analysis of cosmonauts' response times showed that the mental rotation task is not greatly impaired in weightlessness. On the contrary, there are indications of a facilitation as: (1) the average rotation time per degree was shorter inflight than on the ground; (2) this difference seemed to be particularly marked for stimuli calling for roll axis rotations. However several factors may be responsible for this difference which was not obvious in one subject. Further experiments will have to test if this effect is really due to exposure to microgravity.

Adult↗

PubMed1993

Sensorimotor and perceptual function of muscle proprioception in microgravity.

Adaptive properties of the human proprioceptive systems were studied during the French-Soviet orbital flight (Aragatz mission, December 1988). The present space experiment investigated the hypothesis that the modifications of both biomechanical and physiological conditions occurring under microgravity involve considerable reorganization of body perception and postural control. The proprioceptive information originating in muscles is known to contribute, together with visual, vestibular, and sole cutaneous information to postural regulation. Moreover, by specifically activating the proprioceptive channel, muscle vibration is able to elicit both illusory movement sensations and postural responses. This experimental tool was used in microgravity in order to test various aspects of muscle sensory function. Ankle flexor and extensor vibration was applied under different experimental conditions. Quantitative analysis of motor responses was carried out on leg muscle EMG, goniometric, and kinesigraphic recordings. Joystick recordings and astronauts' comments were used to describe the kinaesthetic sensations. The main results were as follows: 1) Under microgravity, the sensitivity of muscle receptors remains unchanged. 2) During the flight, the tonic vibration reflexes (TVR) increased significantly in flexor muscles, which exhibited a sustained tonic activity. 3) The whole-body postural responses normally induced by ankle flexor muscle vibration were suppressed, whereas they remained unchanged or were only reduced when vibrations were applied to the ankle extensor muscles. In all cases, the postural response velocity decreased. 4) A disfacilitation of the vibration-induced postural illusions was observed to occur during long-term exposure to microgravity. These illusions became atypical however. For example: body lift illusion could be induced by tibialis anterior muscle vibration, whereas it was never induced in the controls. The characteristics of the illusory body movements described under normal gravity can be restored by artificially increasing the axial foot support forces during the flight. In conclusion, these data suggest that a functional reorganization of the proprioceptive information processing occurs in microgravity, affecting both perceptual and motor aspects of behavior. It is possible that these proprioceptive adaptations may be partly attributable to the new whole-body propulsive foot functions imposed by exposure to weightlessness and to the adaptation of motor behavior to the third dimension of space.

Adaptation, Physiological↗

PubMed1993

Axial synergies under microgravity conditions.

Fast forward and backward upper trunk movements were analyzed and compared under microgravity and under preflight and postflight conditions. The kinematic analysis showed that the upper trunk movements were accompanied by hip and knee movements in the opposite direction both under microgravity and under normal gravitational conditions. This suggests that the center of mass position with respect to the feet is still regulated under microgravity when the feet are attached to the floor. The EMG analysis during backward movements shows that under preflight conditions a set of muscles (ErSp, BF, Sol) in the back of the body are activated early on. Under microgravity, the early Sol activation was replaced by an early TA activation, which was still present at the first postflight recording and was then replaced by the early Sol activation observed under preflight conditions. This finding shows that the EMG pattern underlying the axial synergies is flexible and that adaptive changes take place both under microgravity and after return to Earth.

Adaptation, Physiological↗

PubMed1993

Gaze control in microgravity. 1. Saccades, pursuit, eye-head coordination.

During the long-duration spaceflight Aragatz on board the Mir station, an experiment exploring the different oculomotor subsystems involved in gaze control during orientation to a fixed target or when tracking a moving target was executed by two cosmonauts. Gaze orientation: with head fixed, the "main sequence" relationships of primary horizontal saccades were modified, peak velocity was higher and saccade duration was shorter in flight than on earth, latency was decreased and saccade accuracy was better in flight. With head free, gaze orientation toward the target was achieved by coordinated eye and head movements, their timing was maintained in the horizontal plane; when gaze was stabilized on the target, there was a trend of a larger eye than head contribution not seen in preflight tests. Pursuit: Horizontal pursuit at 0.25 and 0.5 Hz frequency remained smooth with a 0.98 gain and minor phase lag, on earth and in flight. In the vertical plane, the eye did not track the target with a pure smooth pursuit eye movement, but the saccadic system contributed to gaze control. Upward tracking was mainly achieved with a succession of saccades, whereas downward tracking was due to combined smooth pursuit and catch-up saccades. This asymmetry was maintained during flight in head fixed and head free situations. On earth, head peak velocity was maximal upward, and in flight it was maximal downward.

Electrooculography↗

PubMed1993

Gaze control in microgravity. 2. Sequences of saccades toward memorized visual targets.

The reproduction, in complete darkness, of sequences of 5 horizontal saccades towards previously presented visual targets has been investigated in human subjects on the ground (control subjects) and one cosmonaut in microgravity. The incidence of corrective saccades during the execution of the memory-guided saccades in darkness has been examined. It was quite large for the control subjects (more than half of all saccades), and increased during the flight, while the corrective visually guided saccades incidence decreased. Direction errors occurred in about the third of all sequences on the ground, and this parameter also increased in microgravity. Memory-guided sequences were mostly hypermetric. Whereas the absolute error continuously increased with the target rank, it was not the case with the amplitude ratio, which presented a peak at the third rank, that is, at the middle of the sequence. The accuracy of the reproduction of the sequences did depend on the sequence pattern as much as on the subject. Some learning was observed in repeated reproduction of the same pattern. Although the average error did not change in microgravity, the linear regression coefficient between the visually guided and memory-guided saccades decreased.

Adult↗

PubMed1992

[Strategy and synergy: two levels of equilibrium control during movement. Effects of the microgravity].

Equilibrium is ensured during forward or backward upper trunk movements by displacing the hip and knee simultaneously in opposite directions. When fast movements are performed, a muscle synergy characterized by the early activation of a set of trunk, thigh and leg muscles precedes the onset of the kinematic changes. The question which is addressed concerns the possibility that two levels of equilibrium control might exist during upper trunk movements: the strategy level, which is relatively invariant, is characterized by the displacement in opposite directions of the upper and low segments, and the muscle synergy level at which the strategy is implemented, which may be adaptable to the environmental constraints. When upper trunk movements are performed under microgravity with the subject's feet fixed to the floor of the space cabin, the displacement of upper and lower body segments in opposite directions still occurs, although this is no longer necessary to maintain the equilibrium. This kinematic strategy seems to be aimed at regulating the centre of inertia position with respect to the feet. The muscle synergies associated with these kinematic changes are modified, however, under microgravity. After returning to the ground, the previous synergies do not reappear immediately, but only after a few days. This suggests that a short period of learning is needed to change the synergy. These data are compatible with the hypothesis that two levels of equilibrium control actually exist during upper trunk movements, the strategy level, which is kinematic and invariant, and the synergy level, which is adaptable to the environmental constraints through a short learning process.

Electromyography↗

PubMedDate not supplied

Influence of graviceptives cues at different level of visual information processing: the effect of prolonged weightlessness.

We evaluated the influence of prolonged weightlessness on the performance of visual tasks in the course of the Russian-French missions ANTARES, Post-ANTARES and ALTAIR aboard the MIR station. Eight cosmonauts were subjects in two experiments executed pre-flight, in-flight and post-flight sessions. In the first experiment, cosmonauts performed a task of symmetry detection in 2-D polygons. The results indicate that this detection is locked in a head retinal reference frame rather than in an environmentally defined one as meridional orientations of symmetry axis (vertical and horizontal) elicited faster response times than oblique ones. However, in weightlessness the saliency of a retinally vertical axis of symmetry is no longer significantly different from an horizontal axis. In the second experiment, cosmonauts performed a mental rotation task in which they judged whether two 3-D objects presented in different orientations were identical. Performance on this task is basically identical in weightlessness and normal gravity.

Aerospace Medicine↗

PubMedDate not supplied

Internal reference frames for representation and storage of visual information: the role of gravity.

Experimental studies of visual mechanisms suggests that the CNS represents image information with respect to preferred horizontal and vertical axes, as shown by a phenomenon known as the "oblique effect". In the current study we used this effect to evaluate the influence of gravity on the representation and storage of visual orientation information. Subjects performed a psychophysical task in which a visually-presented stimulus line was aligned with the remembered orientation of a reference stimulus line presented moments before. The experiments were made on 5 cosmonauts during orbital space flight and additionally on 13 subjects in conditions of normal gravity with a tilting chair. Data were analyzed with respect to response variability and timing. On earth, these measurements for this task show a distinct preference for horizontally and vertically oriented stimuli when the body and gravitational axes were aligned. This preference was markedly decreased or disappeared when the body axis was tilted with respect to gravity; this effect was not connected with ocular counter-rolling nor could we find a preference of any other intermediate axis between the gravity and body aligned axes. On the other hand, the preference for vertical and horizontal axes was maintained for tests performed in microgravity over the course of a 6 month flight, starting from flight day 6. We concluded that subjects normally process visual orientation information in a multi-modal reference frame that combines both proprioceptive and gravitational cues when both are available, but that a proprioceptive reference frame is sufficient for this task in the absence of gravity after a short period of adaptation. Some of the results from this study have been previously published in a preliminary report. Grant numbers: 99-04-48450.

Adult↗

PubMedDate not supplied

Does gravity play an essential role in the asymmetrical visual perception of vertical and horizontal line length?

The eye perceives the length of vertical and horizontal lines with an inherent asymmetry. A vertical line having the same length as a horizontal one is usually perceived to be longer. In this experimental investigation we tested the hypothesis that gravity has a direct role in producing the observed perceptual asymmetry. To this end we performed experiments in weightlessness during long-orbital space flights onboard the MIR station. Subjects performed a psychophysical task in which the length of a visually-presented vertical line was adjusted to match the length of a horizontal reference. On Earth, almost all subjects produce errors in adjusting the length of the vertical line, consistently under-estimating the length of the horizontal reference. The asymmetry of perception of the line lengths persisted in weightlessness. From these results we conclude that the phenomena of asymmetry of perception of the lengths of vertical and horizontal lines is not dependent on gravity, but is instead defined by properties of the system of internal representation. Grant numbers: 99-04-48450.

Adaptation, Physiological↗

PubMedDate not supplied

Prolonged weightlessness, reference frames and visual symmetry detection.

We evaluated the influence of prolonged weightlessness on the performance of three cosmonauts to bilateral symmetry detection in the course of a 15-day-long Russian-French mission CASSIOPEE 96 aboard the MIR station. We tested the influence of weightlessness on subjects' performance as a function of the retinal orientation of axis of symmetry. as a function of type of stimuli (closed versus multi-elements shapes) and as a function of visual field presentation (at fixation, left visual field. right visual field). The results indicate firstly a difference between presentation at fixation versus away of fixation. Away of fixation, no effect of microgravity on performance was shown. A hypothesis of hemispheric specialization for symmetry detection was not supported as well. At fixation, an effect of micro-gravity was shown and more interestingly, the effect was quite different as a function of type of shapes used. suggesting that symmetry detection is a multiple-stage process.

Aerospace Medicine↗

PubMedDate not supplied

The face inversion effect in microgravity: is gravity used as a spatial reference for complex object recognition?

Complex objects are better recognized under a specific orientation. When presented upside down, a face, even very familiar, is recognized with greater difficulty than when presented upright ("Inversion effect"). Up to now it was not possible to decide whether the direction provided by gravity or the one provided by the retina and the body constitutes the spatial reference involved in this "Inversion effect". Three cosmonautes learned photographed faces on the ground and had to recognize them both on ground and on flight. Other photographed faces were learned in flight and where presented for recognition on flight. Results show that the Inversion effect is still present on flight for faces that have been learned on ground as well as for those learned on flight. Persistence of the inversion effect in 0-G shows that gravity is not involved as a spatial reference in recognition of faces. Learning and recognition performances of faces learned in flight were significantly lower than performances for faces learned on ground. A possible role of gravity in configural processing, but not in the Inversion effect, is suggested.

Aerospace Medicine↗

PubMedDate not supplied

Motor timing under microgravity.

Five participants were tested on their ability to produce accurate and regular inter-response intervals in the 350 to 530 ms time range. Three of them were members of the French-Russian CASSIOPEE 96 spaceflight mission, and the other two were control subjects tested on the ground. During spaceflight, the target inter-response intervals were increasingly undershot and the timing became more variable (less regular). The increase in the timing variability was mostly attributable to the internal timekeeping processes rather than those involved in motor execution. The results are discussed with reference to the physiological mechanisms possibly underlying the timing of fast serial movements.

Aerospace Medicine↗