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Biomedical subjects

M Littman

Publications and source records attributed to M Littman.

6 recordsLinked to original sources

Culture-proved disseminated cat-scratch disease in acquired immunodeficiency syndrome.

A male homosexual (positive for the human immunodeficiency virus) with a recent cat scratch developed fever, epitrochlear and axillary lymphadenopathy, and retinitis. Subsequently, he developed skin (epitheloid hemangioma) and mucosal lesions (Kaposi's sarcoma), multiple liver abscesses, and pleural effusion. Warthin-Starry stains and/or electron micrographs of lymph nodes and skin lesions demonstrated bacilli characteristic of those associated with cat-scratch disease. Cultures of lymph node, pleural fluid, and liver abscess specimens yielded organisms believed to be the causative agent of cat-scratch disease. We believe that disseminated cat-scratch disease may become an indicator of opportunistic infection signaling acquired immunodeficiency syndrome in a patient who is positive for the human immunodeficiency virus.

Acquired Immunodeficiency Syndrome↗

Varicella pneumonia.

Six normal adults with varicella pneumonia were treated successfully with acyclovir sodium. All patients showed resolution of roentgenographic and arterial blood gas abnormalities. In addition, five of the six patients demonstrated thrombocytopenia that resolved with therapy. Intravenous acyclovir therapy should be instituted as early as possible in patients who may have varicella pneumonia.

Acyclovir↗