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Biomedical subjects

M Loken

Publications and source records attributed to M Loken.

28 records · Page 2Linked to original sources

Radionuclide bolus angiography: a technique for verification of brain death in infants and children.

Fifteen infants and children, 11 of whom had clinical brain death and four of whom were comatose, were evaluated with the radionuclide bolus study and electroencephalography. Clinical criteria for brain death included: (1) absence of spontaneous respirations, (2) absence of cephalic reflexes, and (3) unresponsiveness. Results demonstrated complete correlation among clinical examination, EEG, and radionuclide study in 79% of cases. An approach to the evaluation of the infant or child with possible brain death is outlined utilizing serial examinations, radionuclide bolus study, and electroencephalography. The radionuclide bolus study appears to be a safe, rapid, portable technique which can be used for this purpose in infants and children.

Angiography↗

Distribution of orally administered bromine-82 in tubercular meningitis: concise communication.

Bromine-82 as ammonium bromide (0.6 muCi/kg) was administered orally to 86 children with neurologic manifestations of tubercular meningitis (TBM). The cerebrospinal-fluid-to-plasma activity ratios were obtained at 48 hr. A serum-to-CSF ratio below 1.9 was highly specific for TBM (40 of 42 patients), and only 4 of 44 patients with neurologic disorders other than TBM had ratios below 1.9. An attempt to simplify the diagnosis of TBM was carried out in 44 of the 86 patients by obtaining external counts over the head, heart, and thigh at 4, 24, and 48 hr after Br-82 administration, but these external counts did not distinguish TBM patients from the other patients in our series.

Administration, Oral↗

Effect of ABO incompatibility on the fate in vivo of 111Indium granulocytes.

The effect of ABO incompatibility on the in vivo fate of 111Indium granulocytes was determined. The intravascular recovery and survival (t1/2) and extravascular migration into a skin window of normal-donor granulocytes did not differ in 15 subjects from the values obtained in four controls who received ABO-compatible granulocytes. Nor was the correlation between the ABO antibody titers and the in vivo measurements strongly positive. It is concluded that ABO incompatibility did not alter the in vivo fate of granulocytes.

ABO Blood-Group System↗