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Biomedical subjects

M Longy

Publications and source records attributed to M Longy.

90 records · Page 5Linked to original sources
PubMed1978

[Voluminous hypernephroma of intermittent development. Diagnostic difficulties (author's transl)].

The authors report a case of cancer of the kidney of intermittent development for which nephro-urotomography was negative. They stress the interest of: --preliminary echotomography in patients with palpable masses in the left hypochondrium; --pharmaco-angiography for improved visualization of masses that are only weakly opaque; --a rapid infusion technique, proposed by various authors, which appears to be the most appropriate for the study of this type of mass which is mainly intermittent in its development.

Adenocarcinoma↗
PubMed1976

[Streptozotocin and malignant insulinomas. Apropos of the case. Review of the literature].

In spite of possible toxicity streptozotocin now appears to be the best treatment for malignant islet cell tumour with liver metastases, i.e. inoperable tumours with a poor prognosis either due to extension of the tumour itself or due to hypoglycemic attacks. Out of about 60 patients thus treated, 1 to 2 years survival were obtained. 22 out of 52 patients reported by Broder and Carter are still alive and one may estimate the overall percentage of favourable results at 65%. On the other hand out of another 100 patients treated elsewhere with this antineoplastic agent, only a few cases of carcinoid tumour gave encouraging results. The course of the others was not modified significantly.

Adenoma, Islet Cell↗
PubMedDate not supplied

[Renal lesions in progressive systemic sclerosis. A report on five cases (author's transl)].

Renal lesions are one of the must serious visceral complications of progressive systemic sclerosis: three of the five cases reported died in anuria within a few weeks. A part from this very severe fulminating form, however, cases in which lesions can be demonstrated by pathological examination may produce much milder clinical and biological signs, though still having the same prognostic significance. They can become worse at any moment, either spontaneously, or more often because of other factors such as corticotherapy or pregnancy. A review of the published literature has shown the exact frequency of these lesions and their two principal modes of progression, in both of which the same basic histological changes of proliferation of the intima of the interlobular and preglomerular arteries are found. Kidney function tests can be used to guage the severity and extent of these vascular lesions. It is much more difficult, however, to determine the nature of the initial mechanism causing these lesions. The vascular lesion could be a primary one or may be secondary to an immunological disorder, the exact nature of which has still to be determined.

Acute Kidney Injury↗
PubMedDate not supplied

[Peripheral thrombophlebitis. "Paratuberculous syndrome" (author's transl)].

The authors relate the case of a young North-African man who presented during one month several peripheral thrombophlebitis before a ganglionary tuberculosis of the mediastinum appear. With specific antibiotherapy, the cutaneous lesions disappear and can be so considered as a paratuberculous syndroma.

Adult↗
PubMedDate not supplied

[Perisinusoidal fibrosis in idiopathic thrombopenic purpura].

Perisinusoidal fibrosis of the liver was discovered in a 22 year-old woman with idiopathic thrombocytopenic purpura requiring splenectomy. No etiology of fibrosis could be found. As shown by immunocytochemistry, collagen types I, III, IV, laminin, and fibronectin were increased. Under electron microscopy, numerous collagen bundles and fragments of basement membrane-like material were demonstrated. Perisinusoidal cells loaded with lipids showed several of the characteristics of fibro/myofibroblasts, while the activity and number of Kupffer cells were apparently increased. The exact mechanism of fibrosis in this case remains unknown but it is likely that platelet destruction and/or Kupffer cell hyperactivity played a role.

Adult↗
PubMedDate not supplied

[Plasma cells leukaemia, cryoglobulins and antithrombin (author's transl)].

Although primitive plasma cells leukaemia is uncommon, it still stands in a particular place among malignant lymphoplasmocytary syndroms. It borrows from multiple myeloma and acute leukaemia some of its clinical and biological manifestations. Its course is quickly adverse, its treatment ineffective and the average life expectation is three months.

Aged↗
PubMedDate not supplied

[Sciatica due to chronic spontaneous lumbar epidural haematoma. Report of a case simulating a protruded disk syndrome (author's transl)].

A case of spontaneous chronic lumbar epidural hematoma, in a 70-year-old woman is reported. The clinical, roentgenographic and anatomic findings of this case and of six others found in the available literature are studied. This clinical entity occurs in elderly and must be considered in the differential diagnosis of protruded disk syndromes.

Aged↗
PubMedDate not supplied

[Portal hypertension in schistosomiasis (author's transl)].

Pathological and clinical features of the portal hypertension in schistosomiasis are reminded. The value of the para-clinical investigations (immunology, endoscopy, angiography and hemodynamic controls) is discussed. Medical treatment is limited to parasiticidal action but an attempt to prevent the formation of granulomas by use of antilymphocytic serum has been reported. The surgical intervention is aimed at suppressing the splenomegaly and decreasing the portal hypertension. The indications of the various techniques are discussed (splenectomy, spleno-renal anastosomis associated with splenectomy, vascular porto-caval anastomosis, omentopexy, triple arterial ligation).

Granuloma↗
PubMedDate not supplied

[Is drepanocitic trait asymptomatic? (author's transl)].

With regard to its distribution the drepanocytic trait has a slight pathological incidence and does not appreciably alter the vital prospect. It is not, still, completely asymptomatic and may be, in special pathophysiological conditions, a morbidity and even lethality risk factor. Its connexions with various other diseases should be considered.

Anemia, Sickle Cell↗
PubMedDate not supplied

[Glomerular nephropathy and schistosomiasis (author's transl)].

Glomerular lesion appears frequently in patients with S. mansoni or S. japonicum infection. This nephropathy may bring clinical changes and leads to severe evolution with letal risk. It may be induced or aggravated by the specific treatment but it has then, in most cases, a short duration and a good prognosis. Specific treatment fixed in order to reduce the amount of circulating antigens may be benefic. In some cases, on the contrary, the nephropathy is not reactive to any specific or symptomatic treatment and has an evolution of its own under the action of various factors; the most important is the hepatosplenic damage. Consequently glomerular function must be controlled in patients with schistosomiasis in order to fix the prognosis and the treatment.

Antigen-Antibody Complex↗
PubMedDate not supplied

[Bilharzial myelopathies (case report) (author's transl)].

Report of a case of biharzial myelitis appearing 6/8 weeks after bathing in an infected river. Recovery was complete after medical treatment with niridazol and hycanthone. The authors review the 47 detailed cases previously reported, selected among 60 cases observed from 1905 to 1963. They consider the clinical and pathological aspects and discuss the various pathogenic problems. Treatment requires specific antibilharzial compounds and anti-inflammatory drugs and, in compressive forms, sometimes surgery.

Adult↗