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Biomedical subjects

M Lorentsen

Publications and source records attributed to M Lorentsen.

7 recordsLinked to original sources

The "Scandinavian Star" ferry disaster 1990--a challenge to forensic odontology.

With 158 victims, the fire on board the "Scandinavian Star" was one of the world's worst ferry disasters. A team of identification experts, including dentists, were employed to secure evidence for identification and to remove the victims from the ferry. Four parallel teams, each with 2 dentists, examined and autopsied the victims at the Institute of Forensic Medicine, University of Oslo. Using the INTERPOL Disaster Victim Identification forms and aided by computers, all victims were identified within 17 days. Dental identity could be established in 107 cases (68%).

Adolescent↗

[The airplane accident in Torghatten on May 6, 1988].

On May 6th, 1988, a Dash 7 airplane crashed into the mountain of Torghatten, near Brønnøy-sund in northern Norway. All 33 passengers and the three crew members were killed. The National Identification Commission, including a forensic dentist, was at the disaster site twelve hours later. A dentist and a forensic pathologist worked with the police at the site until all the victims had been found. Three other dentists were responsible for collecting antemortem material and for the postmortem examination of all victims. 32 of the victims, or 89%, could be identified by dental means alone; a higher percentage than ever before reported. The final meeting of the Identification Commission took place five days after the disaster. All the victims were identified on the basis of technical, medical, and dental evidence, and the report signed by each of the three specialist groups. The quality of the dental records was evaluated with respect to requirements set up by the Ministry of Social Affairs in 1983. Dental records had improved since the "Alexander Kielland" disaster in 1980. However, only five of the missing persons had full mouth intraoral radiography, only nine records met the requirements for general information about the patient (birth date and identification number, home and business address, etc), only three had information about earlier diseases, and none had recorded previous dental restorations. Diagnoses were given only for nine persons. The records showed that 21 of the victims had not received any prophylactic treatment.

Dental Records↗

Age assessment based on translucent dentine.

The purpose of this investigation was to examine the relationship between age and the area of translucent dentine (TA) at root apex, and to compare these findings with those obtained by using the methods of Bang & Ramm and of Johanson. The material consisted of 500 teeth, 50 of each tooth type, molars excluded. For statistical analyses an XT microcomputer and SPSS/PC regression programme were used. The correlation between age and ATD varied from 0.83 to 0.57 for different types of teeth. In stepwide multiple regression analyses ATD was preferred to other types of measurement of the translucency. The factors (ATD) and sex contributed significantly to the regression for some types of teeth. Regression analyses using several factors according to Johanson's method resulted in a stronger correlation for most teeth, while the method of Bang & Ramm resulted in a weaker correlation except in the case of mandibular first premolars.

Age Determination by Teeth↗

Effect of intragastric pH on antral gastrin and somatostatin release in anaesthetised, atropinised duodenal ulcer patients and controls.

The synchronous change in the antral release of gastrin and somatostatin into a vein draining the stomach was studied during acidic and alkaline intragastric pH in six anaesthetised duodenal ulcer patients and six controls after atropinisation. No differences in the basal secretion of gastrin and somatostatin were observed among the two groups. Alkaline as well as acidic intragastric pH had no effect on the antral release of somatostatin in duodenal ulcer patients and controls. In contrast, alkaline intragastric pH was associated with a significantly higher antral gastrin release in duodenal ulcer patients than in controls. Acidic intragastric pH was associated with a significantly smaller inhibition of antral gastrin release in duodenal ulcer patients than in controls. These results suggest that atropinised anaesthetised duodenal patients release gastrin abnormally in the presence of acidic or alkaline intragastric pH and that any inverse relationship between antral gastrin and somatostatin release is uncoupled under these conditions.

Adult↗

Altered concentrations of gastrin-releasing polypeptide and somatostatin in fundic and duodenal bulb mucosa of patients with duodenal ulcer disease.

The concentrations of gastrin-releasing polypeptide, somatostatin (SS), and gastrin in extracts of endoscopically obtained biopsies from the fundus, antrum, and duodenum of patients with uncomplicated bile stones (controls) or duodenal ulcer disease were measured with specific radioimmunoassays. The validity of the tissue sampling was confirmed by characteristic and significant differences between gastrin concentrations at the different biopsy sites. Gastrin-releasing polypeptide levels were at their highest in the fundic and duodenal bulb compared to the antrum in controls (p less than 0.01), whereas no differences in gastrin-releasing polypeptide content of the different parts of the stomach were found in duodenal ulcer patients. Compared to controls gastrin-releasing polypeptide in duodenal ulcer patients was reduced in fundic and duodenal bulb mucosa (p less than 0.01). SS levels were highest (p less than 0.05) in the first part of duodenum in controls. Compared to controls duodenal ulcer patients had lower SS concentrations present in fundic (p less than 0.01) and highest SS concentrations present in duodenal bulb mucosa (p less than 0.01). There was no correlation between acid secretion and mucosal gastrin-releasing polypeptide or SS concentrations in any part of the stomach and duodenum.

Adult↗