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Biomedical subjects

M Lotysch

Publications and source records attributed to M Lotysch.

3 recordsLinked to original sources

Meniscal tears of the knee: accuracy of MR imaging.

Before surgery, 277 menisci in 144 knees were examined with magnetic resonance (MR) imaging. They were then examined directly with arthroscopy or arthrotomy. Menisci were graded on a scale of 1-3 according to the character of the intrameniscal MR imaging signal. At surgery, 137 of 154 (89%) menisci exhibiting only grade 1 or grade 2 signal were found to be normal. One hundred sixteen of 123 (94%) menisci exhibiting intrameniscal signal communicating with a meniscal articular surface (grade 3 signal) had tears. If only a grade 3 signal is considered consistent with meniscal tears, then MR findings and surgical findings agreed in 91.3% of menisci. MR imaging can separate surgically significant from nonsignificant meniscal lesions and is useful in the noninvasive preoperative screening of suspected meniscal tears.

Humans↗

Multifocal eosinophilic granuloma involving the common bile duct: histologic and cholangiographic findings.

The multifocal eosinophilic granuloma syndrome (Hand-Schüller-Christian disease) is characterized histologically by focal accumulations of histiocytes and eosinophils. The clinical manifestations of this syndrome reflect the site and extent of these focal accumulations which are usually found in membranous bone, skin, and lung. Significant hepatobiliary disease due to this disorder has not been previously described. We are reporting an adult female with the multifocal eosinophilic granuloma syndrome who developed a mixed histiocytic and eosinophilic infiltration of the common bile duct which resulted in obstructive jaundice. Therapeutic attempts have failed to reverse this process, and the patient has shown progressive intrahepatic biliary tract destruction.

Adult↗

Intertransverse process lumbar arthrodesis with autogenous bone graft.

Fifty-eight patients with a variety of causes of chronic low back pain underwent posterolateral intertransverse process lumbar arthrodesis utilizing autologous iliac bone graft. The overall success rate of achieving fusion was 92%. Most of the failures occurred at the L4-L5 level. The economic and functional improvement as a result of this operation was between 70% and 80%, indicating that achievement of lumbar arthrodesis does not necessarily mean a successful surgical result. Overall improvement did not correlate specifically with levels of fusion or with performance of a laminectomy, but a history of prior low back surgery significantly lowered the success rate, regardless of achievement of a solid arthrodesis. Persisting discomfort at the iliac crest bone graft donor site somewhat lowered the overall improvement rate. Intertransverse process lumbar arthrodesis appears to be a highly satisfactory and perhaps a superior method of achieving lumbar fusion, when arthrodesis is indicated.

Adolescent↗