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Biomedical subjects

M Lough

Publications and source records attributed to M Lough.

10 recordsLinked to original sources
PubMed1989

Diagnosing iron deficiency in a hospital population.

The iron status of four hundred and forty-seven hospital patients was studied in order to assess the efficiency of laboratory tests in diagnosing iron deficiency. One hundred and three patients (23%) were iron deficient on bone marrow examination. The laboratory tests had a low diagnostic efficiency, with either a low diagnostic rate or a high false positive rate. However, serum ferritin, despite a diagnostic rate of 25% did establish the diagnosis with near certainty, avoiding the need for invasive and costly investigations. Serum ferritin should be retained in the laboratory investigation of iron deficiency. Serum iron with iron binding capacity should be removed from the repertoir.

Erythrocyte Indices↗
PubMed1989

Rhabdomyolysis and listeria monocytogenes.

Non-traumatic rhabdomyolysis occurs as a complication of a wide variety of infections and is often discovered as a result of the associated renal failure. We report a case of meningitis due to Listeria monocytogenes, an uncommon cause of infection in adults which was associated with rhabdomyolysis. This confirms a recent first case report of this association.

Female↗
PubMed1988

Effect of head position on distribution of nasal airflow in preterm infants.

Supine preterm infants characteristically adopt a lateral head position; however, it is not known whether this influences the distribution of nasal airflow. Ventilation was measured in 12 healthy preterm infants (postconceptional age 34 +/- 2 weeks) by employing a nasal mask pneumotachygraph that separated airflow between the left and right nasal passages. In the midline supine position, the percent of total tidal volume (%VT) through the right nasal passage ranged from 31% to 64% and varied by less than 5% between active and quiet sleep in any infant. Lateral positioning of the head caused %VT to increase on the dependent side and decrease through the upper nasal passage. When the right side was dependent, mean %VT on that side increased from 52 +/- 9% to 67 +/- 14% (P less than 0.01) and decreased to 43 +/- 10% (P less than 0.05) when the right side was up. In the midline position, the presence of a nasogastric tube caused %VT through the nasal passage with the tube to fall from 54 +/- 8% to 39 +/- 8% (P less than 0.01). The %VT fell farther, to 25 +/- 10% (P less than 0.01), when the nasal passage with the nasogastric tube was up. Despite these changes in VT distribution, total VT remained constant during these maneuvers. We speculate that when supine preterm infants adopt a lateral head position, the decrease in airflow through the upper nasal passage results from partial obstruction of the oropharyngeal or nasopharyngeal airway on that side.

Head↗