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Biomedical subjects

M Louis

Publications and source records attributed to M Louis.

29 records · Page 2Linked to original sources

Adolescent attitudes in a general pediatric hospital. A survey of 87 inpatient admissions.

A study of 87 adolescent patients hospitalized in a large pediatric hospital was made to define their emotional, social, recreational, and educational needs. Open-ended questionnaires were given to the adolescents, their parents, and medical care personnel. Chronic diseases, prolonged hospitalization, multiple admissions, and severity of illness were prominent in the population surveyed. These characteristics were associated with critical patient attitudes toward the physical facilities and psychological atmosphere of the hospital. Knowledge of these attitudes aids in the recreational, vocational, and educational planning for adolescents.

Acute Disease↗

Intensive training of phonological skills in progressive aphasia: a model of brain plasticity in neurodegenerative disease.

Three patients with a typical syndrome of nonfluent primary progressive aphasia (Mesulam's syndrome) were trained daily with a remediation protocol including auditory exercises specifically designed to involve several aspects of phonological processing, a domain known to be specifically affected in the condition. The speech content of the exercises was based on the temporal theory of phonological processes according to which increasing the duration of formant transition should facilitate phoneme discrimination and phoneomic awareness. Significantly improved performance on the trained tasks was demonstrated in the three patients. Improvement further generalized to other tasks such as nonword repetition and reading. We conclude that such results (1) argue for using intensive focused therapy of language impairment in neurodegenerative disorders, (2) may constitute a good model of brain plasticity in neurodegenerative disorders in general, and (3) support theories of phonological processing emphasizing temporal features of the auditory signal.

Aged↗

[Preliminary dosimetry study of the Orsay synchrocyclotron proton beam with a view to applying it therapeutically].

Using proton beams for treatment of malignant tumors of the eye allows high dose irradiation of the tumor volume with negligible irradiation of the surrounding critical structures. Actually, the clinical results reported from the Boston or Villigen groups which have experience of such a technique, are impressive. In France, it is planned to use soon 200 MeV proton beams from the Orsay synchrocyclotron 20 km from Paris. Therefore, a feasibility study has been conducted during year 1988, consisting of a dosimetric analysis of the characteristics of the Orsay proton beams. It was concluded that only simple modifications were necessary to make the beam clinically available for protontherapy and more specifically for treatment of uveal melanomas.

Animals↗