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Biomedical subjects

M Lucas

Publications and source records attributed to M Lucas.

At least 253 records · Page 14Linked to original sources
PubMed1972

Study of chromosomes in the newborn after ultrasonic fetal heart monitoring in labour.

The effect of continuous-wave ultrasound on the chromosomes of newborn infants has been investigated. Twenty-four women were studied during labour. The fetal heart was monitored by a Sonicaid FM2 monitor applied to the abdomen, and continuous monitoring undertaken for intervals varying from 1 hour 5 minutes to 9 hours 25 minutes. There was no increase in the number of chromosome aberrations in cultures of blood taken from the insonated babies when compared with controls.

Chromosome Aberrations↗
PubMed1972

Effect of ultrasound on chromosomes of lymphocyte cultures.

In-vitro experiments have been undertaken to assess the effect of ultrasound at diagnostic and therapeutic levels on chromosomes of human lymphocyte cultures. The frequency used was about 2 MHz. The intensity was that of diagnostic level, 23 mW/cm(2), which was increased stepwise to 3.5 W/cm(2). The time of exposure varied from two to eight hours. No difference could be detected between the numbers of cells with aberrations in the insonated and control cultures, but aggregation of red cells was observed at high intensities.

Cell Aggregation↗
PubMed1972

Neurological abnormalities in the 'cri-du-chat' syndrome.

An unusual case of the cri-du-chat syndrome is described in a 6½ year old boy, who, as well as attacks of stridor and choking, showed disorders of spatial perception and cerebellar signs in the form of nystagmus, clumsiness of the hands, and ataxia. Pyramidal signs were also present. He was only mildly retarded mentally. Psychological testing showed that he had a severe deficit for number processing, and also constructional apraxia. Surprisingly, his vocabulary was quite good, as was his reading capacity. Chromosome analysis showed a very small deletion of the short arm of the group B chromosome. In infancy this diagnosis may be suspected because of the high-pitched cry and attacks of stridor and choking. In late childhood, when the signs may be only of a neurological disorder, its recognition may be difficult without confirmation from chromosome studies. The neurological features of this disease are reviewed.

Cerebrospinal Fluid Proteins↗