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Biomedical subjects

M Lucian

Publications and source records attributed to M Lucian.

At least 19 recordsLinked to original sources

An outbreak of Shigella sonnei infection due to contamination of a municipal water supply in northern Israel.

An epidemic of more than 8000 cases of Shigella sonnei infection took place in four adjacent urban communities which share the same water supply. The epidemic was caused by massive faecal contamination of the drinking water due to a leak from a broken main sewage pipe into an adjacent drilled well. The infecting organism in most cases was S. sonnei colicine type 6, biotype A, which showed a high rate of multiple resistance to commonly used antibacterial drugs. Most of those affected were children less than 15 years of age. Among adults the attack rates were higher in women. Most cases were mild, only 91 patients being admitted to hospital. One 5-year-old child died.

Adult

An outbreak of typhoid fever due to contamination of the municipal water supply in northern Israel.

An outbreak of typhoid fever followed a large outbreak of dysentery in northern Israel. Both outbreaks resulted from contamination of a drilled well that supplied water to the municipal water system. The well was contaminated with sewage from a broken main-pipe coming from Shefaram (an Arab town). The outbreak of typhoid involved 77 persons, of whom 75 were hospitalized. In 67, phage-type C1 (the phage type dominant in Shefaram since the 1950s) was isolated. The incubation period was relatively long, between 12 and 40 days (median 22) following exposure. Over 50% of the cases were children aged 0 to 14, and only two patients were older than 35 years; the sex ratio among the patients was 1:1. The incidence rate in Shefaram was 2.3 times higher than in the Krayot (outlying suburbs of Haifa). This difference was due mainly to the high incidence in young females in Shefaram. The opposite was observed during the outbreak of dysentery, when the attack rates of the disease were higher in the Krayot. Relapses occurred in 12% (9 cases). This outbreak demonstrates the potential that still exists for serious outbreaks due to contamination of the municipal water supply.

Adolescent