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Biomedical subjects

M Lurati

Publications and source records attributed to M Lurati.

8 recordsLinked to original sources

[Multiple sclerosis and personality aspects (author's transl)].

In a sample of 85 multiple sclerosis patients an increase of the objective neurological degree of severity of the illness resulted in a significant decrease of manifold psychometrically recorded functions of intelligence (verbal and non-verbal intelligence). Of the personality characteristics registered by questionnaire only depression proved significant, but numerically slightly positive correlation with the degree of severity of the illness. The correlations between degree of severity and personality characteristics, as aggressiveness, sociability, neuroticism, extraversion were not significant. The personality-psychological results were especially interpreted and discussed with regard to the therapeutic consequences.

Adult↗

[Ganglions a rare cause of isolated peripheral nerve lesions].

Extra- and intraneural ganglionic cysts rarely involved peripheral nerves. They are found in the neighbourhood of large joints. The ulnar nerve is affected most often by extraneural cysts at the wrist. Intraneural cysts prefer the peroneal nerve at the tibiofibular joint. Ganglionic cysts as a cause of peripheral nerve damage are often overlooked, mainly because they are not considered as a cause of pain, paresis or sensory changes. Surgical treatment is recommended.

Cysts↗

[Immunosuppressive treatment of polymyositis].

Azathioprine (150 mg daily) was given to 14 patients with polymyositis. Most of the patients also received prednisolone (initial dose 80-40 mg daily, maintenance dose 15-5 mg daily). Some patients additionally received 6-mercaptopurine, methotrexate and (or) cactinomycin. Symptoms practically disappeared in three patients, while in four there was marked improvement, in four others moderate improvement occurred. Four patients who were improved had previously received long-term treatment with high doses of corticoids but without response. There were three deaths; treatment had definitely failed in one, in the other two the duration of treatment had been too short. Results were best in patients under 40 years of age in whom the disease had followed an acute or subacute course: in two of seven in this group corticoid treatment had previously failed. This fact, as well as the observation of exacerbations when immuno-suppressives were reduced, indicate the value of this form of treatment.

Acute Disease↗

[Intraneural ganglion in the peroneal nerve].

Report of a case of an intraneural ganglion in the peroneal nerve. Reviewing the literature this rare case of peroneal nerve palsy is discussed. The therapy consists in an operative decompression of the nerve by excision or incision of the ganglion cyst.

Humans↗