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Biomedical subjects

M M Agaev

Publications and source records attributed to M M Agaev.

At least 19 recordsLinked to original sources

[Efficacy of combined use of fosinopril and propranolol in acute myocardial infarction].

Echocardiography, Doppler echocardiography and ECG mapping were used in 40 patients aged 30-70 years with first anterior Q-wave myocardial infarction (MI) for the study of effects of combination of fosinopril and propranolol (20 patients) in comparison with propranolol alone (20 patients) on hemodynamics and size of myocardial damage. The use of fosinopril and propranolol was associated with lowering of systolic and diastolic blood pressure without development of hypotension, reduction of sum, number of leads with, and amplitude of ST-segment elevations, and improvement of parameters of left ventricular function. In propranolol treated patients favorable changes of all these parameters were less pronounced. Inhospital clinical course of the disease was also better in patients treated with fosinopril and propranolol.

Adrenergic beta-Antagonists↗

Plasmapheresis in overall treatment of renal immune diseases.

Polymorphism of the clinical picture manifested in pregnancy induced nephropathies necessitates the development of special immune methods of diagnosis, prevention and overall treatment. The changes in cellular and humoral immunity disclosed in this group of patients may serve as a starting point for elucidating the mechanism underlying pathogenesis of the disease and complications. Complex therapy, including medicinal preparations, dietotherapy and plasmapheresis contributes to normalizing the clinical course of pregnancy, correcting the immunologic status and decreasing the incidence of complications in the postpartum period.

Antibody Formation↗

[The microvascular bed of the nail matrix in patients with chronic uremia].

The microvascular bed of the nail matrix was studied in 118 patients with chronic uremia and 25 healthy persons. It was revealed that in chronic renal failure due to chronic nephritis, the changes in microcirculation were more pronounced. Prolonged arterial hypertension led to a graver derangement of the vascular sector of the microcirculatory bed. Red blood cell aggregation depended on the stage of uremia, anemia and impairment of water-electrolyte metabolism. The data obtained on biomicroscopy of the eyeball conjunctiva correlated with the data on capillaroscopy of the nail matrix. The latter technique makes it possible to control the disease and efficacy of the treatment.

Adolescent↗

[Ultrasonic scanning in chronic renal insufficiency].

A total of 315 patients with chronic renal insufficiency (CRI) were investigated in order to study the potentialities of ultrasound scanning in early diagnosis of obstructive nephropathy. The susceptibility of the test was 96%, specificity--94%. Due to its simplicity and noninvasiveness it can be recommended as a method of screening in renal obstruction irrespective of renal function. It provides an opportunity to rapidly identify groups of patients who need urgent surgical aid to restore urine passage or conservative therapy. In the absence of ultrasound signs of obstructive diseases further x-ray examination is inappropriate. The use of ultrasound scanning as the first diagnostic procedure simplifies and facilitates the examination of CRI patients, preventing undesirable complications, associated with radiocontrast methods of kidney visualization.

Humans↗

[Effect of hemodialysis on blood hormone and lipid levels in patients with chronic kidney failure].

The task of the study was to investigate the effect of systematic hemodialysis on lipid and hormonal metabolic indices in patients with chronic renal insufficiency (CRI). In 83.3%, patients with CRI at the terminal stage demonstrated lipid disorders noted against a background of noticeable hormonal imbalance and characterized by high levels of insulin, parathormone, cortisol, somatotropin in the blood serum and a low level of triiodothyronine in the blood. Systematic hemodialysis did not result in significant changes in lipid metabolism. Lipid metabolic disorders in patients with CRI at the terminal stage were detected in 91.7% of cases. Changes in the level of hormones under study were characterized by a decrease in thyroxine concentration thus weakening thyroid function in CRI patients.

Adult↗

[Parathyrin and calcitonin in patients with chronic renal insufficiency].

Examination of 37 patients with chronic renal insufficiency (CRI) has shown that an increment of CRI gravity is accompanied by an increased degree of disturbance of the phosphoric-calcium metabolism and parathyroid hormone and calcitonin (CT) levels. The authors regard a high calcitonin level in the presence of secondary hyperthyroidism as a result of CT retarded catabolism and an increase in the level of immunoreactive but biologically inactive CT. Multimodality conservative therapy to restore phosphoric-calcium balance in CRI should be aimed at the suppression of parathyroid gland function.

Adolescent↗