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Biomedical subjects

M M Aliev

Publications and source records attributed to M M Aliev.

16 recordsLinked to original sources

[Tissue pressure in patients with phlebogenic edema].

This paper describes the results of tissue pressure measurement according to the Emmet technique in the subcutaneous fat at phlebogenic edema in 31 patients with lower extremity varicosity. The changes in the pressure were recorded over a length of 5-10 after needle impaction. The rate of tissue fluid resorption was measured. The indicators appeared normal in 16% of patients, absorption was accelerated in 39%, and deceleration of absorption was marked in 45% of patients. In the event of decelerated resorption, chronic edema was observed more frequently. The rate of saline resorption in health exceeded 4.8-fold the rate of tissue fluid absorption. In valvular insufficiency of the deep veins, this indicator is up to 4.8-fold as increased. Cessation of tissue fluid and/or saline resorption points to tissue swelling at the microcirculatory level. The given technique allows to diagnose latent edema, to objectively evaluate the patient tissue response to a specific drug and elastic appliance, to work out the well-founded indications for phlebectomy, especially in young people. Also, it enables the assessment of the results of surgical intervention and making the early diagnosis of disease recurrences.

Blood Flow Velocity↗

[Prophylaxis of recurrent multiple echinococcosis of the liver in children].

The article presents an experience with treatment of 47 children aged from 3 to 14 with multiple echinococcosis of the liver. The authors have made a comparative analysis of the antiparasitic remedies and of a wide spectrum bactericidal solution of Betadin. The results of microscopic, histological and electron microscopic investigations have shown Betadin to be highly effective and harmless for the intraoperative prophylactics of recurrent echinococcosis. It is expedient to use Betadin for multiple echinococcal lesion of the liver in children.

Adolescent↗

[The efficacy of organ-preserving operations on the spleen in portal hypertension in children].

Under analysis are results of treatment of 38 children with liver cirrhosis. Operations were performed in 25 patients, in 13 children decompensating shunts were put between the vessels of the splenic and left renal veins. Based on the assessment of the clinical effect the authors made a conclusion that in children with portal hypertension and symptoms of hypersplenism the creation of a spleno-renal anastomosis with the retained spleen is an effective measure and considerably reduced risk of postoperative complications.

Adolescent↗

[The function of the liver mitochondria in rats with experimental cirrhosis undergoing an organ-preserving operation on the spleen].

The effect of splenectomy and of spleen-preserving operation with suture ligation of the left gastric artery on the functional status of liver mitochondria was studied by using 102 white male-rats of mixed population with experimental cirrhosis. The obtained data made it evident that in the immediate postoperative period (from 1 to 3 weeks after the procedure) in the animals of both the first and the second series, the disorder of energetic regulation of mitochondria hepatocytes respiration and the decrease in phosphorylation efficiency had the same tendency, which were seemingly caused by stress-action of the operative trauma. The data accumulated in the more distant postoperative period (8 weeks after the procedure) indicated that the resection of the lower splenic pole in combination with supplementary liver arterialization improved essentially the functional status of mitochondria hepatocytes and was more beneficial in contradistinction to splenectomy.

Animals↗

[Clinical aspects and surgery of fibrocholangiocytosis in children].

Fifty one children with a diagnosis of fibrocholangiocystosis (FCC) were examined. A degree of circulatory blockade in the portal vein system in FCC was established to be one of the factors conditioning a severity of the course of the disease and its prognosis. With increase in duration of the disease and age of a child, the cirrhotic process in the liver and its complications are aggravating. The esophagogastric bleeding with the incidence as well depending on duration of the disease is the most severe and life-threatening complication. Our experience with operative treatment of FCC is indicative of the necessity to perform early interventions, and of a high effectiveness of creating the vascular anastomosis with preservation of the spleen.

Adolescent↗

[Functional condition of the liver after surgical treatment of cirrhosis in children as revealed by hepatoscintigraphy].

Scintigraphy with colloid 99mTc (56 cases) and the radiopharmaceutical preparation 99mTc--HIDA (43 cases) was performed in children with early and developed cirrhosis of the liver to study the functional condition of the hepatic Kupffer's and parenchymal cells in the long-term periods after surgical treatment. Increased activity of the parenchymal cells and inactivation of Kupffer's cells were revealed after splenectomy. The formation of a portocaval shunt and denervation of the hepatic artery promoted activation of hepatocyte functioning in these patients.

Child↗

[A 99mTc-colloid study of the intrahepatic blood flow in liver cirrhosis in children].

Hepatoscintigraphic investigations were conducted in 63 patients aged 3 to 15 to study the features of intrahepatic blood flow and degrees of its compensation in children with liver cirrhosis of different stages. 99mTc-colloid was employed as a radiopharmaceutical. Disproportions of scintigraphic liver images showed close correlation with clinico-biochemical and morphological signs of the severity of disease. Subcompensation and decompensation of the organ blood flow and reticuloendothelial system in children with developed and terminal stages of liver cirrhosis are characterized by prolonged blood RP inhibition, a decrease in the total clearance of radioactive colloid, a progressively reduced index of liver clearance, and an increase in a colloid uptake by the spleen.

Adolescent↗