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Biomedical subjects

M M Ansari

Publications and source records attributed to M M Ansari.

30 records · Page 2Linked to original sources

Efficacy of ivermectin in controlling Strongyloides westeri infections in foals.

Twenty-eight foals whose dams were treated IM with ivermectin (200 micrograms/kg of body weight) on the day of parturition were compared with 35 foals whose dams were administered only the vehicle. The effect of ivermectin on the vertical transmission of Strongyloides westeri and foal heat diarrhea was determined by a comparison of results obtained in the 2 groups. Foals from treated mares had significantly fewer S westeri eggs per gram of feces from 17 to 28 days postpartum. There were no differences observed in the frequencies of severity of foal heat diarrhea between the treated and control groups. In another experiment, using the same foals, 32 foals were treated IM with ivermectin (200 micrograms/kg) at 21 days of age and were compared with 31 foals administered only the vehicle. Significantly fewer S westeri eggs were recovered from the ivermectin-treated foals on day 26 to day 32, the completion day of the trial.

Animals↗

Effects of washing on the bacterial flora of the stallion's penis.

Six stallions were subjected to extensive cleansing of the penis and prepuce with water, Ivory Soap and water, or Betadine surgical scrub and water. The stallions were all washed for 14 days, and then allowed 14 days respite. This pattern of washing and resting was repeated consecutively. Swabs were taken from all 7 stallions twice weekly and semen was collected once a week for bacteriological examination. All forms of cleansing altered the bacterial flora of the stallion's penis; the Ivory Soap tended to encourage the replacement of the normal flora with coliform organisms, while Betadine favoured the growth of Pseudomonas aeruginosa and Klebsiella spp. This experiment showed that the systematic washing of a stallion's penis will cause the normal flora to be replaced with pathogens and potential pathogens.

Animals↗

Colibacillosis in neonatal lambs: onset of diarrheal disease and isolation and characterization of enterotoxigenic Escherichia coli from enteric and septicemic forms of the disease.

A lamb ligated intestinal segment (LIS) test was adapted to determine the enterotoxigenicity of Escherichia coli isolates obtained from fecal and blood specimens from neonatal lambs with overt diarrheal disease. The lamb LIS was distended by 28 of 80 (37%) isolates from fecal specimens from 23 affected lambs. Enterotoxigenic E coli isolations were made from 10 of the 23 lambs examined. Isolates of E coli were made from the blood of 17 of 76 (22%) animals with severe diarrheal disease. Distention of the lamb LIS was caused by 3 of 39 (7.7%) isolates from 2 of 17 lambs with E coli septicemia. All lambs (n = 266) that were born during a 4-day period in an intensified shed lambing operation and that were not given prophylactic antibiotic therapy developed diarrheal disease within 28 hours of birth. Signs of enteric disease appeared in lambs born during inclement weather in a significantly (P less than 0.001) shorter period than in those born during mild weather conditions.

Animals↗

Hepatitis in patients with surgical complications of pulmonary tuberculosis.

During last six years, 2250 patients were treated in Cardiothoracic Unit for thoracic complications of pulmonary tuberculosis. During isoniazid/streptomycin/ethambutol treatment, 2 patients out of 710 (0.28%) developed hepatitis. During isoniazid/rifampicin/ethambutol therapy, 18 patients out of 1540 (1.17%) suffered from jaundice; all these patients were above 30 years of age, and many had gross anemia (Hb less than 9 gm%), hypoalbuminemia (less than 3 gm%) and radiologically far-advanced disease in comparison to those who did not develop jaundice (p less than 0.05). Jaundice subsided completely after discontinuation of isoniazid and/or rifampicin which were re-instituted successfully after recovery without recurrence of hepatitis. It is suggested that the development of hepatitis does not warrant total withdrawal of these two highly effective bactericidal drugs but they should be tried again cautiously after recovery from jaundice.

Adult↗

Corrosive pyloric stenosis--a report of two cases.

Two unusual cases of post corrosive pyloric stenosis in adults are reported. Both the cases were diagnosed clinically and confirmed by barium meal examination. Patients were discharged following anterior gastrojejunostomy. Follow-up examination did not reveal any problem. However, both of them are undergoing regular dilatation for the associated oesophageal stricture.

Adult↗