PubMed Health⌕ Search

Biomedical subjects

M M Boskovic

Publications and source records attributed to M M Boskovic.

5 recordsLinked to original sources
PubMed2000

Surgical template for completely edentulous patients.

Implant angulation is of utmost importance for fabrication of esthetic, hygienic, and functional prostheses, even in the treatment of completely edentulous patients. Most mandibular surgical templates are not reliable because of a lack of stability resulting either from severe resorption of the mandible or from the interference of mucoperiosteal flaps elevated during surgery. This article describes a technique for fabrication and surgical application of a stable template for the completely edentulous mandible. By combining the mandibular template with a maxillary duplicate denture, the problem of lack of stability can be overcome. A consistently reliable reference for implant placement in the edentulous mandible, specifically in relation to implant angulation (trajectory), can be obtained.

Acrylic Resins↗
PubMed1997

Experimental peri-implant tissue breakdown around hydroxyapatite-coated implants.

This study monitored experimental peri-implant tissue breakdown around hydroxyapatite (HA)-coated titanium dental implants. Thirty-two HA-coated cylindrical implants, in groups of two, were bilaterally inserted in the posterior maxilla and mandible in 4 Macaca mulatta monkeys. Two months after healing-abutment connection, a 2-month plaque control program was initiated. Clinical and radiographic recordings and peri-implant submucosal microbial samples were then obtained (baseline). Cotton ligatures were next placed around the healing-abutments and plaque control measures were abandoned. Clinical and radiographic recordings were repeated at 5 and 10 months post-baseline. Microbial samples were repeated at 10 months post-baseline, and ligatures were removed. Clinical, radiographic, and microbial examinations were again repeated at 11 months post-baseline. Mean modified plaque index (mPI; P < 0.01), gingival index (G]; P < 0.01), and bleeding on probing (BOP; P < 0.05) scores increased over the plaque accumulation period. The mPI, and GI scores decreased after ligature removal (P < 0.001). Mean probing depth (PD) and clinical attachment level (AL) increased between baseline and the 5- and 10-month examinations (delta PD 3.0 mm; delta AL 2.7 mm; P < 0.05). PD values were reduced following ligature removal (P < 0.05). AL values and BP scores remained unchanged. A significant negative correlation was found between induced defect depth and width of keratinized mucosa at baseline (P = 0.03). At baseline, the submucosal microbiota was dominated by coccoid cells. Following ligature placement, the microbiota included a large proportion of Gram-negative anaerobic rods, predominantly Porphyromonas gingivalis, Bacteroides forsythus, and Fusobacterium species as well as beta-hemolytic streptococci. Ligature removal had a limited effect on the composition of the submucosal microbiota. This non-human primate study indicates that ligature-enhanced plaque accumulation is a precursor of progressive peri-implant tissue breakdown around HA-coated implants. The associated microbiota resembles that of peri-implantitis and destructive periodontal disease in humans. This preclinical model may be useful to study modalities aimed at arresting peri-implant tissue breakdown and at regeneration of bone in peri-implantitis defects.

Alveolar Bone Loss↗
PubMed1992

Solving the problem of violated intermaxillary space caused by poor pre-planning and improper placement of endosseous implants: a case report.

Every dental implant patient needs thorough evaluation and pre-surgical planning. It is imperative for the practitioner to have absolute knowledge of the implant system to be used. Nevertheless, sometimes we find ourselves in very difficult, almost unrestorable, situations. Often, we cannot rely on the implant manufacturers, and we have to be ready to customize some parts in order to solve difficult clinical situations. This case report shows how customized magnet keepers were fabricated by use of plastic IME's as casting patterns in order to solve the problem of violated intermaxillary space.

Dental Alloys↗
PubMedDate not supplied

Bone formation and reosseointegration in peri-implantitis defects following surgical implantation of rhBMP-2.

This study was designed to evaluate bone formation and reosseointegration following surgical implantation of recombinant human bone morphogenetic protein-2 (rhBMP-2) in peri-implantitis defects. Hydroxyapatite-coated dental implants were placed bilaterally in the mandibular and maxillary premolar area in four rhesus monkeys and were allowed to osseointegrate for 1 year. Cotton ligatures were then placed around the healing abutments, and plaque was allowed to accumulate for 11 months. Resulting circumferential peri-implantitis defects exhibited a large intrabony and horizontal component. At reconstructive surgery, peri-implantitis defects in contralateral jaw quadrants were randomly assigned to receive rhBMP-2 (0.43 mg/mL implant volume) in an absorbable collagen sponge carrier or a carrier control. The animals were sacrificed 4 months postsurgery, and block sections were prepared for histometric analysis. Summary statistics included means calculated per animal. Paired t tests were used to evaluate differences between experimental conditions (n = 4). Defect depth amounted to 3.4 +/- 0.9 mm and 3.2 +/- 0.9 mm for rhBMP-2 and control defects, respectively. Vertical bone gain in rhBMP-2 defects (2.6 +/- 1.2 mm) was significantly greater than in controls (0.8 +/- 0.8 mm; P < .01). Reosseointegration within the confines of the defect for rhBMP-2 defects (29.0 +/- 10.5%) differed significantly from that in the control (3.5 +/- 2.5%; P < .01). Reosseointegration within the extent of newly formed bone averaged 40.0 +/- 11.0% in rhBMP-2 defects as compared to 8.9 +/- 7.8% in the control (P < .01). Osseointegration in resident bone amounted to 69.5 +/- 6.9% and 72.6 +/- 8.0% for rhBMP-2 and control defects, respectively. There is significant evidence that rhBMP-2 has potential to promote bone formation and reosseointegration in advanced peri-implantitis defects in a demanding nonhuman primate model.

Alveolar Bone Loss↗