Biomedical subjects

M M Erian

Publications and source records attributed to M M Erian.

6 recordsLinked to original sources

PubMed1998

The effects of danazol after endometrial resection--results of a randomized, placebo-controlled, double-blind study.

We report the results of a controlled, randomized, prospective, 'double blind' evaluation of the effect of danazol treatment in 120 patients after hysteroscopic endometrial resection. After endometrial resection, the women were allocated to 1 of 3 groups: Group A- placebo; Group B - high-dose danazol (600 mg daily); Group C - low-dose danazol (200 mg daily) plus placebo tablets. Tablets were specifically manufactured for the study, were identical in appearance, and were supplied in individual prepackaged boxes. The duration of treatment was 3 months and patients' compliance was noted. Amenorrhoea, dysmenorrhoea and premenstrual tension symptoms were assessed for each group by 1 or 2 independent gynaecologists at follow-up intervals of 6 weeks, 3, 6 and 12 months. A statistically-significant increased rate of amenorrhoea was found in patients who received treatment with the higher-dose danazol (600 mg day) following endometrial resection. While not statistically significant, the same trend was noted with the low-dose danazol. This result should influence our clinical management of women with menorrhagia, and the long-term results on the same cohort of patients are awaited with interest.

Adult↗

PubMed1996

Transcervical endometrial resection.

STUDY OBJECTIVES: To determine the safety and efficacy of endometrial resection, and to provide an indicator of the operative problems and treatment outcomes. DESIGN: Prospective study. SETTING: Academic practice tertiary care setting. PATIENTS: One hundred twenty-six consecutive women undergoing endometrial resection because of menorrhagia, who wished to retain their uterus. INTERVENTION: Hysteroscopic endometrial resection performed as a day procedure. MEASUREMENTS AND MAIN RESULTS: In 126 women, 2 cases of uterine perforation were readily identified on the operating monitor screen; they had no serious sequelae. Three patients had heavy uterine bleeding, which was controlled by intrauterine tamponade. No women had other serious complications. CONCLUSION: Hysteroscopic endometrial resection is a safe, successful, and cost-effective treatment of menorrhagia.

Adult↗

PubMed1995

Female circumcision.

Three cases of female circumcision are presented together with a literature review. Unfortunately, this procedure frequently results in genital mutilation. Treatment with deinfibulation enables restoration of the external genitalia and vagina. Obstetric and gynaecological complications have been documented, but emotional and psychological effects may be difficult to assess. These women should be treated without bias and with sensitivity.

Adult↗

PubMed1994

A new laparoscopic aspiration technique for ovarian dermoid cysts.

A new method for aspirating benign dermoid cysts enables removal of the collapsed cyst wall without the need for extending laparoscopic incisions or opening the pouch of Douglas. The technique has been used by one of the authors in 10 patients with good effect and minimal or no spillage of dermoid cyst contents into the peritoneal cavity.

Anti-Infective Agents, Local↗

PubMed1994

Unusual contents of a dermoid cyst of the ovary removed by laparoscopy.

Benign cystic teratoma (dermoid cyst) of the ovary is a common pathological entity. Usually, the cyst contains representative tissues of the 3 embryonic germ cell layers: ectoderm, mesoderm and endoderm. Sebaceous material, hairs, cartilages, teeth, even thyroid tissue are frequently observed. In this case, the tumour was a well-formed jaw and tongue, and was successfully removed via the laparoscope.

Adult↗

PubMed1971

Trimethoprim-sulphamethoxazole in acute brucellosis.

Eight patients with proved brucella infection were treated with trimethoprim-sulphamethoxazole. The dose varied from two to four tablets given twice daily for three weeks. Clinical response was rapid and all patients were asymptomatic and afebrile within two to seven days of starting therapy. Three patients relapsed clinically and bacteriologically within three weeks of ending treatment. There were no side effects of the treatment. It is suggested that the treatment be continued for at least six weeks to prevent relapses.

Adolescent↗