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Biomedical subjects

M M Kosenko

Publications and source records attributed to M M Kosenko.

6 recordsLinked to original sources

[Quantitative, functional and cytogenetic characteristics of lymphocytes and various indicators of immunity in persons participating in the decontamination work at the Chernobyl nuclear power plant].

Immunologic and cytogenetic investigations conducted in subjects, who had been engaged in liquidation of consequences of the Chernobyl NPS catastrophe, during the first months after their work was finished, showed decreased content of large granulo-containing lymphocytes and serum IgM in the blood, their levels were completely recovered 3 years later. A complex of unfavourable factors attending radiation (stress, changes in the way of life, chemical actions etc.) played an important role in the genesis of these changes.

Accidents↗

[Assessment of radiation risk of leukemia induction based on the analysis of the consequences of population irradiation in Southern Ural].

The authors provide the results of long-term investigations of the consequences of environmental pollution from the military nuclear plant in the Southern Urals. Altogether 28,100 individuals who received substantial doses of external and internal radiation in the Techa riverside in the early fifties were entered into the study. The increase in the leukemia incidence as compared with unexposed controls has been confirmed on a statistical basis. The majority of excess cases of leukemia were recorded within the 5th to the 20th year after irradiation and may be attributed to the acute and chronic granulocytic types. The level of leukemia risk on the basis of the Techa river data is evaluated as 0.48-1.10 per 10(4) persons/years/Gy.

Air Pollution, Radioactive↗

[Lethal developmental defects in the offspring of a population living in a territory with traces of radioactivity].

The paper is concerned with the materials of a study of long-term effects of irradiation at small doses of a limited population, taking by way of example lethal developmental defects in descendants. In 1957 a radioactive trace was formed as a result of an explosion of a tank with highly active radiochemical by-products. The population in this area was exposed to irradiation. Mortality from lethal developmental defects in the descendants was analyzed. The data obtained have shown that the effect on the gonads of external irradiation at doses of 0.1-0.5 Sv (33,500 persons) revealed no statistically significant variations in the mortality of the descendants from developmental defects as compared to the controls.

Abnormalities, Radiation-Induced↗

[The medical sequelae of the radiation accident in the Southern Urals in 1957].

As a result of an accidental outburst of long-lived radionuclides at the nearest zone of the trace, a dose rate of gamma-radiation was several dozen CGy/h and in the open country at some populated areas it was 0.1 CGy/h. The evacuation of 10730 persons permitted a decrease of possible radiation doses 2-24-fold. A follow-up of persons who had been exposed to the highest effective equivalent doses of radiation before the evacuation revealed unstable indices of leukocytes and platelets (however they were within normal variations) in the first 2 years. Morbidity and mortality rates among the adults, the rates of congenital diseases and pediatric mortality did not differ from the control values. The rate of families having children born from persons aged 10 to 30 at the time of the accident did not differ from the similar rates for the USSR; this rate was lower by 5-10% than the control values for persons aged 0 to 9 at that time. Standardized birth rates in the study group (31 x 8,10(-3)) were much higher than in the control group (18 x 4,10(-3)).

Accidents↗