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Biomedical subjects

M M Kuftinec

Publications and source records attributed to M M Kuftinec.

53 records · Page 3Linked to original sources

Nutrition in growth and development of oral tissues.

The development of teeth, salivary glands, and other oral tissues can be seriously compromised by a deficiency of a number of essential nutrients. Because nutritional stress during critical development periods may decrease the ultimate resistance of the oral tissues to challenge, the prevention of disease and maintenance of oral health are intimately dependent on the nutrient supply during development. Appropriate dietary counseling, particularly with reference to critical developmental times and intake of essential nutrients, can insure optimal oral tissue development.

Calcium↗

Bone growth in the neonatal rat. II. Biochemical aspects of bone mineral incorporation.

Long bones and mandibles from neonatal rats were studied to characterize the mechanisms regulating their growth and to describe the patterns of bone mineral acquisition. Mineral uptake was determined by measuring the rates of incorporation of radioactive calcium (45Ca) into three metabolic pools within, or intimately surrounding, the bone. The incorporation into the pool of protein-bound calcium was low throughout the neonatal period, accounting for no more than 1% of the total calcium uptake during this period. The ionized calcium concentration, which was low throughout, increased at the time when formation of the mineral phase was found to be high. The largest fraction of the mineral, the complexed calcium, showed a gradually increasing rate of incorporation, lasting approximately until the age of weaning. The two bony tissues differed somewhat in the slopes at which the incorporation rates changed. From these studies of bone growth, it appears that the process of bone mineralization starts around the time of birth, gradually gains intensity and is maximal between approximately 10 and 18 days. It is speculated that the ionized calcium fraction may be the precursor of mineral formation.

Age Factors↗

Effect of edgewise treatment and retention on manidbular incisors.

This study consisted of analyzing clinical records of fifty cases treated for correction of Class I malocclusion with varying degrees of bimaxillary protrusion and anterior mandibular crowding. Thrity of these cases required extraction of all four first premolars. Parameters characterizing changes in position of mandibular incisors during treatment with edgewise appliances and during retention and shortly afterward were studied. All the parameters indicated rather similar changes for the nonextraction and the extraction groups. The relapse of anterior mandibular crowding was significantly larger (p less than or equal to 0.05) in the nonextraction group. The IMPA and interincisal angle changed significantly more in the extraction group. Upon testing for validity of the mesiodistal to faciolingual indices, it was determined that they predicted stability of the achieved alignment of mandibular incisors. There were, however, individual cases in both groups which did not follow the central tendency. It was observed that the mesiodistal diameters of mandibular incisirs were somewhat larger in the extraction cases. There was only one pair of parameters that showed a moderately high intercorrelation (r equals 0.68); that was between correction of the anterior crowding and relapse of the intercanine expansion. It was observed that the more correction took place, the more readily expanded canines would relapse. An over-all impression is that the mandibular incisors change little in their position to each other and relative to the other structures of the mouth. The question remains: Is this due to our ability to control them well, or due to an inability to move and maintain them in their new position?

Bicuspid↗

Investigation of a circannual rhythm in nasopharyngeal airway patency in children.

We have studied nasopharyngeal adenoids on standardized cephalometric radiograms of 25 children in each season. While individual subjects showed changes ranging from 1-17% throughout the year, a synchronized circannual rhythm could be described for the girls only. Similar changes were observed in boys, although a synchronized group rhythm could not be ascertained. No clear explanation for this apparent sexual dimorphism is known at this time, but different hormonal influences are likely. Evaluation of the nasopharyngeal airway (NPA) patency is thus affected by the season in which a cephalogram is taken. It should be noted that due to the described circannual rhythmicity, a single determination of the adenoid masses may be an insufficient and misleading indicator of the NPA obstruction. Etiology and clinical significance of these rhythmic changes need to be explored further.

Adenoids↗

The impacted maxillary canine: I. Review of concepts.

This first of the two papers dealing with impaction of the maxillary canines explores the etiology of the most frequently encountered and treated dental impactions. Developmental events believed to play a significant role in the etiology of impactions, together with diagnostic methods of localization, as well as the available preventive measures are reviewed. Our second paper deals with the clinical management of the maxillary impacted canines.

Child↗