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Biomedical subjects

M M Mvula

Publications and source records attributed to M M Mvula.

4 recordsLinked to original sources

Is knowledge about signs and symptoms of preterm labor related to low birth weight?

The intent of this study was to explore the relationship of patient knowledge about the signs and symptoms of preterm labor and low birth weight. To this end, 538 women were interviewed in the postpartum period. Five aspects of preterm labor knowledge (abdominal tightness, vaginal discharge, cramping, diarrhea, and bleeding) were sought, along with standard demographic information. Data were analyzed as dichotomous variables and compared using odds ratios. Logistic regression was chosen to calculate adjusted odds ratios, including only those factors found to be associated with low birth weight. Patient knowledge of each varied from 46 to 87% for the five items. Only one third knew all five areas. Knowledge of the importance of abdominal tightness, vaginal discharge, and cramping were associated with a reduction in low birth weight, as was knowledge of all five aspects. However, regression analysis failed to support a significant association with any of the five areas alone or when considered as a group. The low sensitivity of the relationship between patient knowledge and low birth weight and the lack of correlation after regression suggest that programs focusing on enhanced patient education may have limited benefits.

Abdomen↗

Relationship of phencyclidine and pregnancy outcome.

OBJECTIVE: To analyze the relationship of phencyclidine (PCP) and pregnancy outcome, as judged by low birth weight (< 2,500 g). STUDY DESIGN: A retrospective, case-control study of PCP use was conducted among pregnant women who delivered at a large hospital in New Orleans. PCP use was ascertained by urine screening at the time of obstetric admission. Three control patients were selected for each case, matched for age, parity and month of delivery. The study intended to address the prevalence of low birth weight. RESULTS: Between January 1990 and June 1996, 13,653 patients delivered. Of these, 23 were identified as PCP users. PCP users had smaller infants (2,698 vs. 3,011 g, P < .05); that may have been accounted for by a reduction in gestational age (37.3 vs. 38.3 weeks, P = NS). The users were more likely to give histories of using tobacco, alcohol or marijuana but not cocaine. Syphilis and diabetes mellitus were found more often in the study group. Multisubstance use was also common in the study group. The prevalence of low birth weight was not statistically different for the study and control groups. CONCLUSION: PCP use was not associated with an increase in low birth weight. When identified, patients using PCP require comprehensive evaluation.

Adult↗

A comparative evaluation of collaborative prenatal care.

OBJECTIVE: To evaluate the effectiveness of an advanced-practice nurse-obstetrician collaborative prenatal practice. METHODS: A group of 194 consecutively enrolled medically low-risk obstetric patients was identified between January 1, 1994 and December 31, 1994 at Neighborhood Pregnancy Care, a collaborative-practice site. An equal number of medically low-risk patients attending the Louisiana State University obstetric clinic at the Medical Center of Louisiana at New Orleans was selected randomly from among those registering the same month. The two groups were compared on the primary outcome variable, low birth weight. Data were analyzed by chi2, Fisher exact test, t test, and regression models. RESULTS: We compared 179 collaborative-care and 181 university patients with retrievable information. By univariate analysis, collaborative-care patients more often were teenagers and black, and less likely to be married or employed. Collaborative-care patients had more prenatal visits and were more likely to participate in Medicaid, but less likely to deliver at the Medical Center of Louisiana at New Orleans. Birth weight and gestational age at delivery were greater. Both delivery before 37 weeks (7.3% versus 17.7%, P < .001) and birth weight less than 2500 g (8.9% versus 19.3%, P < .001) were less common. When differences identified at the initial obstetric visit were considered, multivariate weighted logistic regression confirmed the importance of prenatal care at the collaborative-practice program for low birth weight (odds ratio [OR] 0.37; 95% confidence interval [CI] 0.19, 0.71) and preterm delivery (OR 0.36; 95% CI 0.16, 0.78). When all differences were entered, low birth weight remained a significantly less likely occurrence at the collaborative-practice site (OR 0.46; 95% CI 0.23, 0.92). CONCLUSION: An advanced-practice nurse-obstetrician collaborative practice may be implemented successfully and lead to acceptable perinatal outcomes, as judged by low birth weight and prematurity.

Academic Medical Centers↗

Is knowledge of health behavior associated with low birth weight?

OBJECTIVE: To examine the relationship of patient knowledge concerning seven health behaviors identified by the U.S. Public Health Service Expert Panel and low birth weight. METHODS: Interviews of 538 women delivering at an inner-city hospital in New Orleans were conducted. Information concerning patient characteristics, health behavior knowledge, and birth weight was collected. Data were analyzed as dichotomous and compared using odds ratios. Logistic regression was chosen to calculate adjusted odds ratios, including only factors found to be associated with the tested end point, low birth weight. RESULTS: A majority of women knew all seven health behavior items. Individual items were known by > or =80% of respondents. Knowledge associated with low birth weight included avoidance of alcohol and drugs, taking of prenatal vitamins, and following a proper diet. Information on all seven was not associated with a reduction in low birth weight. Other factors found to be associated with low birth weight included inadequate prenatal care, absence of health insurance (primarily Medicaid), and a prior low birth weight infant. Logistic regression confirmed both the importance of the last three factors, and the lack of association with health knowledge about all seven items. CONCLUSIONS: Knowledge concerning health advice behavior recommended by the U.S. Public Health Service was more widely known than previously thought. While individual components were associated with a reduction in low birth weight, overall knowledge was not.

Adult↗