Acute alcohol withdrawal syndrome in a newborn.
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Biomedical subjects
Publications and source records attributed to M M Nichols.
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An unusual case of tracheobronchial scald associated with head and neck scald is reported. A five-month-old infant, lying on his back with his face under the hot water tap, not only sustained head and neck scalds, but also swallowed and aspirated hot water. Burns of the mouth, pharynx, trachea, major bronchi, and bronchides ensued.
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Sudden infant death syndrome (SIDS) infants have significantly thicker and more cellular bronchiolar walls than control infants of similar age. A morphometric study of 25 SIDS and 18 control infants was undertaken to measure the bronchiolar wall thickness using a Cue-2 image analysis system. A mathematical formula (relative index) was used to compare the thickness of bronchioles of varying diameter. Data analysis using a nested design two-way analysis of variance and covariance of the measured bronchioles showed a significant difference between the SIDS and control infants with a P value less than .001. Manual counting of the cells in the bronchiolar walls and data analysis using an unpaired two-tailed t test showed that the SIDS infants had a significantly greater number of cells than control infants (P less than .01). Our preliminary results indicate that the cells in the bronchiolar wall are either peripheral nerve-derived (Schwann cells) or Langerhans cells. We postulate that these cells are increased in number in response to chronic hypoxia in SIDS infants.