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Biomedical subjects

M M Rubin

Publications and source records attributed to M M Rubin.

At least 37 records · Page 2Linked to original sources

Fibrosarcoma of the mandible: a case report.

Fibrosarcoma is a relatively rare malignant tumor found in the head and neck region. Pain and swelling are the two most frequent symptoms, but other findings include paresthesia, trismus, loosening of teeth, ulceration, swelling, and pathological fracture. This case report underscores the importance of early diagnosis and detection of oral neoplasms to minimize therapeutic intervention.

Adult↗

Assessment and management of cervical intraepithelial neoplasia.

Although cervical intraepithelial neoplasia (CIN) once was thought to be a clinical problem primarily for older women, data reveal an alarming rise of this condition among younger women. The gains made in decreasing the incidence of cervical cancer have been tempered by the steadily increasing incidence of its precursor state, CIN. Because of increasing evidence of the association of the human papillomavirus (HPV) with cervical cancer and CIN, this virus is of particular concern. Colposcopy is a valuable method for evaluating CIN that has been indicated on Pap, as well as for identifying HPV. Since having an abnormal Pap and undergoing colposcopic examination may be stressful, the clinician can play a significant role in helping the client cope with the process of evaluation and treatment of abnormal Paps in addition to controlling cervical cancer.

Colposcopy↗

Treatment of stage II endometrial carcinoma.

The optimal management of stage II carcinoma of the endometrium remains to be established. We reviewed our experience in treating 42 patients with stage II endometrial cancer by surgery, radiation, or combined radiation and surgery at the Hospital of the University of Pennsylvania. The overall 5-year survival was 47.6%. The 5-year survivals of patients treated by surgery only, radiation only, or combination radiation and surgery were 68.5, 36.5, and 46.1%, respectively, which were not significantly different. Histologic grade was found a significant prognostic factor but type of cervical involvement was not. Major complication rates were similar in each treatment group. We conclude that the majority of patients with stage II endometrial carcinoma are best treated by combination radiation and surgery, but in a select subset of patients, radical hysterectomy and lymphadenectomy constitute a reasonable treatment option.

Adenocarcinoma↗

Treatment of caustic ingestion.

This article reviews the management of patients following caustic ingestion. The initial care is conservative, consisting mainly of IV antibiotics and steroids. Patency of the airway is of immediate concern and achieved via either intubation or tracheostomy. Early intervention with oral splint therapy is recommended to minimize scar contracture. It is important that the oral and maxillofacial surgeon be acquainted with the primary care of such patients, as well as with the subsequent management of the secondary complications of decreased stomal opening, loss of the mucobuccal fold, and limitation of tongue movement.

Alkalies↗

Acute transient sialadenopathy associated with anesthesia.

Five cases of acute transient sialadenopathy associated with the administration of anesthesia are described in this article. In each case, the patient's straining on the endotracheal tube was followed immediately by firm swelling of one or more of the salivary glands. The facial swelling was resolved within 24-four hours without treatment.

Acute Disease↗