[Liver involvement in podagra].
In 65 patient suffering from podagra, liver function was found to depend on a number of aggravating factors (alcoholic drink use, obesity). Liver function disorders were detected in 1/4 of the patients examined. Alterations in enzymic activity were recorded in 44% of podagra patients, using alcohol. The level of AlAT was 0.78 +/- 0.21 mumol/l versus 0.54 +/- 0.02 in the control group (p less than 0.05), that of AcAT 0.60 +/- 0.13 mumol/l versus 0.41 +/- 0.01 in the control group, and that of xanthine oxidase 110.9 +/- 3.89 units versus 87.4 +/- 1.4 in the control group. In 22.2% of podagra in the disease history, alterations in liver function were also detectable, which was likely to be due to the podagra process itself. On scanning of 36 patients suffering from podagra, 23 persons manifested diffuse and 6 focal liver injury.