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Biomedical subjects

M M Solov'ev

Publications and source records attributed to M M Solov'ev.

At least 37 records · Page 2Linked to original sources
PubMed1978

[Cause of failures in the cryodestruction of malignant tumors of the oral mucosa and tongue and the ways to increase the effectiveness of cryogenic action].

On the grounds of clinical observations over the use of cryodestruction on 109 patients with malignant neoplasms of maxillofacial localization it has been found that the recurrence took place mainly in cases when neoplasm was localized close to the large vessels (e.g. the lingual artery). The authors suggest to increase the cryoeffect through the artificial weakening of the speed of the blood flow in the vessels of the regions exposed to freezing. With this object in view, special experiments have been carried out and their results are described in the article.

Animals↗
PubMed1977

[Osteoplasty of the lower jaw with composite grafts].

Experimentally on 32 white rats of Wistar line and on 15 outbred dogs the authors studied plastic properties and healing processes of composite transplants, employed for replacement of mandibular defects. It was found that the composite transplant consisting of an allogenic lower jaw, treated according to "os purum" type, and an autobone was more resistant to infection, showed no rejection response and possessed adequate plastic properties. This enable the authors to apply the mentioned combination clinically in 7 patients with mandibular defects from 3.5 to 15 cm. Favourable results were obtained in every patient: the anatomical shape of the jaw and its functioning was restored, a good cosmetic effect was gained.

Animals↗
PubMed1977

[Influence of physiologically active substances isolated from the thymus on the course of the wound process following cryodestruction in rats].

Experiments were conducted on 40 male albino rats subjected to general irradiation in a dose of 200 R, to study the influence of "thymarin"--a compound obtained from the thymus of cattle (representing a complex of three physiologically active polypeptide fractions with an average mol wt 10 000) on the course of local wound process after cryodestruction of the hard palate mucosa. The preparation was injected subcutaneously for ten days after cryodestruction. The experimental data obtained pointed to a favourable influence of "thymarin" on the course of regenerative processes, as shown by accelerated rejection of necrotic tissues, more rapid epithelialization of wound surface, and prevention of secondary infection.

Animals↗