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Biomedical subjects

M M Uddin

Publications and source records attributed to M M Uddin.

17 recordsLinked to original sources
PubMed2005

Is serum C-reactive protein really a sensitive stress marker in Bangladeshi people.

The present study was done to determine the serum C-reactive protein (CRP) concentration in normal subjects and patients suffering from infection, psychiatric disorders and of surgery. A total number of 55 subjects within 18-55 years age were selected from Mymensingh Medical College Hospital during the period from July 2003 to June 2004. Normal subjects as control were 13 and 42 comprised the group experimental. According to different types of stress the experimental group was further divided in to four subgroups: infection, psychiatric, pre and post surgery. Serum CRP concentration was measured by Immunoturbidimetric method from each subject. Statistical analyses were done by using Student's ' t' test. Statistically significant rise of serum CRP was observed in infection, psychiatric disorders and post surgery group in comparison to control group (P< 0.001). The study indicated that subjects with infection, psychiatric disorder and post surgery stage were in stressful conditions that resulted increased synthesis of CRP by liver cells due to Hypothalamopituitaryadrenal (HPA) axis hyperactivity and immune mediated inflammation.

Adolescent↗
PubMed2005

Infant outcomes of gestational diabetes mellitus.

This study was carried out in Mymensingh Medical College and Hospital, Mymensingh. The work, which lasted for one year commencing in July 2003, was designed to find out and compare the infant outcomes of gestational diabetes mellitus (GDM) with a view to reducing the complications. Forty cases of GDM with single pregnancy were selected as experimental group, while forty other cases of pregnant women without GDM constituted the control group. Questionnaire and observation charts were the research instruments. Statistical analyses were done manually. It was retrieved that the offspring of GDM mothers had a higher risk of macrosomia, neonatal jaundice and respiratory complications. The perinatal mortality rate was also more in GDM cases. However, befitting measures for prevention, treatment and management of GDM may be taken up to ameliorate the situation.

Case-Control Studies↗
PubMed2005

Glycemic status in women using combined oral contraceptive pill.

This study was undertaken to determine the effects of low-dose combined oral contraceptives(OCs) containing 30 gm Ethinyl estradiol with 150 microg Levonorgestrel on carbohydrate metabolism by a glycaemic variable -- fasting blood glucose level. It is now known that impairment of carbohydrate metabolism is a potential risk factor for cardiovascular disease and other metabolic disorder. Sixty women age between 15-35 years using OCs served as experimental group and thirty age matched hormonal contraceptive non users were selected for control group. Experimental group was again subdivided into OCP (Oral contraceptive pill) users for last one year group, three year group and five year group. The result showed that there were no significant differences on blood glucose level between users and non-users women. It is concluded that the cyclic administration of monophasic low dose OCs did not altered blood glucose levels and there by have no additional adverse impact on women health reaffirming the ongoing oral contraceptive pill distribution program.

Adolescent↗
PubMed2005

Pregnancy associated complications of mothers with gestational diabetes mellitus.

This study was conducted in Mymensingh Medical College and Hospital, Mymensingh. It lasted for one year commencing in July 2003, and was designed to find out and compare the outcomes of gestational diabetes mellitus (GDM) with a view to reducing the complications. Forty cases of GDM with single pregnancy were selected as experimental group, while forty other cases of pregnant women without GDM constituted the control group. Questionnaire and observation chart were the research instrument in this study. Statistical analyses were done manually. It was found that the GDM mothers had a higher risk of complications like pre-eclampsia, hypertension, urinary tract infection and cesarean delivery. On the basis of these findings, however, appropriate measures for prevention, treatment and management of GDM may be adopted for better pregnancy outcomes.

Diabetes, Gestational↗
PubMed2004

Studies on clinical pattern of glomerulonephritis.

A prospective study of primary glomerulonephritis covering two and half years period was done at Dhaka Medical College Hospital & IPGMR, Dhaka from June 90 to July 92. A total of 100 cases were included in this study. All of the patients were of 13 years and above, clinically diagnosed, and by laboratory investigations, the diagnoses were established. In this study, we have tried to find out age incidence, sex ratio, possible aetiological factors, common clinical presentation, biochemical parameters and histological typing of primary glomerulonephritis.

Acute Kidney Injury↗
PubMed2003

Factors affecting the early discharge of the indoor psychotic patients - a sociodemographic survey in a specialized institution.

This is descriptive type of cross-sectional study carried out among 100-discharged patient in a specialized psychiatric hospital. Socio-demographic study revealed that among 100 cases 97% were admitted with schizophrenia, 35% with bipolar affective disorder, 10% with psychotic depression, 5% with brief psychotic disorder, 2% with schizoaffective disorder, 1% with schizophreniform disorder. Their mean hospital stay was 19 days with highest mean hospital stay in schizoaffective disorder (32 days). Mean age of the patient was 26.5 years and highest no. of patients (52%) were in 20-25 years age group. Male female ratio of the patient was 3.761: 1. Occupational distribution of the cases family history of psychiatric illness in 1st degree and 2nd degree relatives was present and mean duration of illness was 73.4 months. Statistically significant independent variables that have impact on length of hospital stay (Dependent patient (p<0.007); electro convulsive therapy (p<0.005); family history of psychiatric illness (p< 0.046), Treatment with typical antipsychotic drugs (p <0.033); treatment with atypical antipsychotic drugs (p <0.000), Rx with combination of typical and atypical antipsychotic drugs (p<0.012); treatment with depot preparation (p<0.011); Treatment with combination of oral antipsychotic drugs (p<0.003) and patient hailing from rural area (p<0.026).

Adolescent↗
PubMed2002

Turner syndrome: a case of gonadal dysgenesis.

An eighteen years old girl came from Ishargang, Mymensingh complaining of short stature, absence of development of breast, lack of menstruation and other secondary sex characters. She was found in infantile appearance with a height of 123 cm, body weight of 28 kg. She had short, broad, webbed neck, cuvitus valgus, absence of development of breast, axillary and public hairs with infantile external genitalia. Hormonal profile revealed high level of LH and FSH, low level of estrogens. Ultrasonography revealed uterine hypoplasia and ill defined gonadal streaks, Karyotype showed typical 45, X0 pattern. She was diagnosed as a case of gonadal dysgenesis due to Turner syndrome.

Adolescent↗
PubMed1988

An analysis of the empirical relationship between contraceptive prevalence and fertility in Bangladesh.

"This paper presents an empirical relationship between contraceptive prevalence and fertility [in Bangladesh]. It also shows how much the level of contraceptive practice is to be raised to reach a targeted level of fertility on the assumption that all other intermediate variables that influence the fertility remain constant. Regression analysis has been used to measure the relationship. A formula derived from Bongaarts's model is used to find the level of contraceptive practice required to reach a targeted fertility." Data are from a variety of sources, including four contraceptive prevalence surveys carried out between 1979 and 1985, the 1975 Bangladesh Fertility Survey, and official statistical sources.

Asia↗
PubMed1985

Phorbol ester stimulates catecholamine synthesis in isolated bovine adrenal medullary cells.

In isolated bovine adrenal medullary cells, the phorbol ester 12-O-tetradecanoyl phorbol 13-acetate (TPA), an activator of protein kinase C, stimulated [14C]catecholamine synthesis from [14C]tyrosine, but not from [14C]DOPA. This stimulatory effect of TPA on [14C]catecholamine synthesis was not dependent upon extracellular Ca2+, and TPA did not affect the uptake of 45Ca2+ or the release of catecholamine by the cells. TPA also did not affect the intracellular cyclic AMP (cAMP) level. 4 alpha-Phorbol 12, 13-didecanoate, which is not an activator of protein kinase C, did not stimulate the synthesis of [14C]catecholamine from [14C]tyrosine. The stimulatory effect of TPA on [14C]catecholamine synthesis was additive with that of carbamylcholine, but not with that of dibutyryl cAMP (DB-cAMP). From these results, it was suggested that protein kinase C is involved in the regulation of tyrosine hydroxylase activity and that this regulatory mechanism might be similar to that involving cAMP.

Adrenal Medulla↗
PubMedDate not supplied

Factors influencing child mortality levels in rural Bangladesh: evidence from a micro study.

"This paper examines the factors that affect child mortality [in rural Bangladesh] by using a multivariate technique. The results suggest that mother's access to education and health care facilities are important determinants of child mortality. The access to maternal and child health programs and visit by the health workers were also related to low childhood mortality...." (SUMMARY IN FRE AND ITA)

Asia↗
PubMedDate not supplied

Islam and family planning acceptance in Bangladesh.

One frequently cited barrier to more widespread adoption of family planning in Moslem countries is religious opposition. To examine the depth and extent of such opposition in Bangladesh, 106 men who had been identified by their wives as religiously opposed to family planning were interviewed. Unexpectedly, 26 percent of the "opposing" husbands reported that they were current users of a contraceptive and an additional 50 percent, although not practicing, said they were in favor of family planning. Of the alleged "opposers," only 23 percent said they opposed family planning on religious grounds. One-fourth of this last group were able to cite specific islamic injunctions against family planning. It appears on the basis of these data, which were collected in the religiously conservative area of Lakshimipur, that the perception of widespread Islamic-based resistance to contraception in Bangladesh is not founded in fact.

Bangladesh↗