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Biomedical subjects

M M Wong

Publications and source records attributed to M M Wong.

At least 73 records · Page 4Linked to original sources
PubMed1975

A survey of Sarcocystis in nonhuman primates.

Of the 375 wild-caught Old World and New World monkeys examined in this survey, 79 (21%) were infected with Sarcocystis, while 369 laboratory-born animals were negative. Four strucutrally different types of sarcocysts were observed; 2 were probably new species. New host records were recognized for 4 species of Asian macaques, 3 Africican cercopithecids, and the New World Saimiri sciureus.

Animals↗
PubMed1969

Studies on immunization against Brugia malayi infection in the rhesus monkey.

Recent studies on immunity to helminthic infection have shown that some degree of protective immunity may be stimulated by inoculations of attenuated living worms or their metabolites. The present experiments were designed to observe the effects of attempted immunization in the rhesus monkey by the use of attenuated infective larvae of Brugia malayi.Some effect was observed in animals inoculated with larval incubate, in which microfilaraemia did develop, but at low levels and for short durations. However, the most strking finding was that persistent immunity to challenge infections (expressed as failure to cause microfilaraemia) was obtained in animals vaccinated with large numbers (200) of infective larvae attenuated by X-irradiation at 20 000 R.Experiments with different numbers of larvae attenuated by different doses of irradiation suggest that there is an optimum combined effect of these two factors in eliciting functional antibody in a quantity sufficient to prevent patent infection in Malayan filariasis.

Animals↗