Biomedical subjects
Publications and source records attributed to M M Zitouna.
The authors report two cases of papillary carcinoma of a thyreoglossal duct cyst. In both cases, the thyroïd gland was normal. Clinical manifestations are not specific and the diagnosis is usually made by histopathologic examination which reveals in the majority of cases a papillary carcinoma. When loco-regional or metastatic extension are absent surgical excision of the cyst is sufficient.
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One case of abdominal actinomycosis is reported which was detected in a diabetic patient three years after surgery for duodenal peptic ulcer. Gastric actinomycosis is very rare and is usually discovered during surgery for gastric mass. The role of surgery as a predisposing condition to infection is discussed. The diagnosis rely on the characterization of the bacteria in cultures from a discharging wall fistula and on histopathologic examination which reveals the characteristic actinomycotic granules.
The authors report the first two cases of Echinococcus multilocularis observed in Tunisia, in two patients from the North-West of the country, who never travelled abroad. The diagnosis was reached by histopathologic examination of a partial hepatectomy section. The appearance of this disease in this geographic area where unilocularis hydatic cyst is endemically present needs further epidemiologic study.
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Cystic meso-omental lymphangiomas are uncommon benign tumors. When symptoms arise, the correct diagnosis is only exceptionally considered. These tumors may be revealed by a variety of clinical pictures which, in fact, are not specific. Cystic meso-omental lymphangiomas are usually diagnosed in pediatric patients, although they may arise in adults. The four patients who are reported on are adults. Diagnosis was established upon histopathological examination of specimens removed during surgery or autopsy. Data from a review of the medical literature provides a basis for a clinical and above all pathological study of cystic meso-omental lymphangiomas. Prognosis is usually favorable although it is dependent upon the conditions of surgical management.
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The authors point out three cases of appendicular taeniasis disease into an analytical retrospective study of 5,000 appendicectomies. In these 3 cases the parasite does not induce important processes level with the appendix. The localisation of the parasite is very rare.
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The authors studied 61 bone marrow biopsies carried out in cancerous patients, presumably suffering from a bone metastasis and before any treatment. They feel that quantitative and qualitative changes in the bone marrow may be considered to be an indirect diagnostic indication of metastatic spread.
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We report 65 cases of MALT gastric lymphomas. HP was looked for with Giemsa and Whartin Starry stains. Immunohistochemistry was done with PAP method. Anti-HP treatment was used in 9 cases. 38 were of low grade of malignancy, 23 were high grade, 4 were high grade with a low grade component. The mean age was 51.5 years, the sex ratio 1.5. Epigastric pain was the most frequent feature (87.7% of cases). Endoscopically, low grade lymphomas presented as unique or multiple ulcerations (55.3% of cases) with antral localisation (52.6% of cases). 60% of our patients were stage IE, of which 61% had low grade lymphoma, 18% were at stage II2E, 10% at stage III and 10% at stage IV. From 23 operated patients, 29% had early lymphoma which was low grade malignant in 71.5% of cases, and 71% had lymphomas which were widely spread beyond the submucosa. HP was found in 63% of cases. Histologic regression of two early lymphomas of low grade malignancy was achieved after HP eradication.