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M Madentzidis

Publications and source records attributed to M Madentzidis.

2 recordsLinked to original sources

Functional outcome after experimental cauda equina compression.

Spinal nerve roots often sustain compression injuries. We used a Wistar rat model of the cauda equina syndrome to investigate such injuries. Rapid transient compression of the cauda equina was produced using a balloon catheter. The results were assessed by daily neurological examination and somatosensory evoked potential (SEP) recording before surgery and ten weeks after decompression. Compression of the spinal nerves induced changes in the SEP which persisted for up to ten weeks after decompression, but it had no effect on the final neurological outcome. Our study shows the importance of early surgical decompression for cauda equina syndrome.

Animals↗

Involvement of the caudate nucleus in the modulation of the brain somatosensory evoked potentials.

The participation of the caudate nucleus in the modulation of the cortical somatosensory evoked potentials was investigated in male rabbits. The power spectra of the somatosensory evoked potential recorded from the scalp in the intact animal was compared with that recorded after kainic acid lesion of specific regions of the caudate nucleus (i.e., anterior and or posterior portions of the head of the nucleus) and the "destructive" interference patterns which appeared were investigated. It was found that the caudate's head modulates the waveform at the end of the early phase of the cortical somatosensory evoked potentials, i.e., the period from 20.8 ms to 29.4 ms. These results suggest that the caudate nucleus is part of the sensory pathways belonging to the nonspecific projection system and participates in the integrating processes of the somatosensory information.

Animals↗