Don't treat nurses as if they were invisible.
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Biomedical subjects
Publications and source records attributed to M Magee.
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Sensitization of UV-irradiated mice with alloantigen results in suppression of the immune response against that antigen. The induction of delayed hypersensitivity and the proliferative response of spleen cells isolated from the UV-irradiated mice are significantly suppressed. We demonstrate here that the rejection of tissue allografts is also suppressed after treatment of the recipient animals with UVR. Two signals, UVR and antigenic sensitization are required to suppress allograft rejection, exposure to UVR alone is not sufficient. The resulting immunosuppression is specific for the antigen used to sensitize the UV-irradiated animal. The induction of graft-versus-host disease was also significantly suppressed when spleen cells from UV-irradiated alloantigen sensitized mice were used to reconstitute lethally irradiated allogeneic mice. Our interpretation of these data is that the antigen-specific suppressor T cells present in the spleens of the UV-irradiated alloantigen sensitized mice are suppressing the immune response against the alloantigen. Thus, the induction of suppression by UVR serves as a novel method of suppressing graft rejection.
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Care of the patient with MI who receives thrombolytic therapy is an exciting challenge for the emergency nurse. By interrupting the process of cellular ischemia and necrosis, thrombolysis can salvage jeopardized myocardial tissue and lead to better patient outcome. Nursing interventions can help prevent possible complications of thrombolytic therapy, such as bleeding, dysrhythmias, and reocclusion. In addition, careful and continuous patient assessment enables the nurse to detect and manage these complications immediately.