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Biomedical subjects

M Mahjoub

Publications and source records attributed to M Mahjoub.

10 recordsLinked to original sources

Standard 12-lead ECG versus special chest leads in the diagnosis of right ventricular myocardial infarction.

The case of a 60-year-old woman with an acute inferior transmural myocardial infarction associated with a right ventricular myocardial infarction provided an opportunity to compare the performance of the 12-lead electrocardiogram (ECG) and the right chest leads in the diagnosis of infarction of the right ventricle. While the right chest leads revealed unequivocal evidence of ischemic injury emanating from the right ventricle, the standard leads II and III showed changes compatible with inferior myocardial infarction; familiarity with vectorial interpretive concepts of ST segment deviations could provide a hint of an associated right ventricular involvement. This report is presented at a time of renewed controversy regarding the necessity of special ECG leads in the diagnosis of acute right ventricular infarction in the routine emergency department environment.

Electrocardiography↗

Correlative studies of heart rate and heart rate variability indices from five consecutive ambulatory electrocardiogram recordings in patients with coronary artery disease.

BACKGROUND: Reproducibility of heart rate (HR) and heart rate variability (HRV) indices from ambulatory electrocardiograms (AECGs) is a prerequisite for their use as predictors or monitors of disease progression, or response to therapeutic interventions. HYPOTHESIS: This study sought to determine the stability over time of HR and HRV indices in patients with coronary artery disease. METHODS: Five AECGs, recorded at 1-week intervals in 21 clinically stable patients, were used to calculate minimum, average, and maximum HR, and three commonly used HRV indices in data samples of 15, 30, 60, 120, daytime and nighttime intervals (complete data were available on 17 patients). RESULTS: All parameters studied were stable over time (p = NS). Diurnal variation was found only for the average and maximum HR, with values being higher for daytime than for nighttime. Intercorrelations of the HR and HRV indices were poor and varied among the five AECGs, suggesting that these parameters reflect different aspects of HRV. The HR and HRV variables calculated from short-time intervals correlated poorly with the corresponding information from 24-h recordings, and such relationships varied among the five AECGs. CONCLUSIONS: Thus, HR and HRV indices from five consecutive AECGs recorded at 1-week intervals are reproducible. The poor intercorrelations between pairs of the studied indices suggest that none of these parameters can be used as surrogate of the others. Finally, the poor performance of HR and HRV indices, deriving from short-time intervals, indicate that they cannot be employed in lieu of parameters calculated from 24-h AECGs.

Aged↗

The paradox of negative exercise stress ECG/positive thallium scintigram. Ischemic ST-segment counterpoise as the underlying mechanism.

A 62-year-old woman with exertional angina underwent an exercise thallium-201 stress test. She exercised for 4 minutes on the treadmill using a modified Bruce protocol, reaching 94% of her predicted maximal heart rate, and stopped because of chest pain and fatigue. No ST-segment depression was detected at peak exercise or in the recovery period. In contrast, the thallium-201 myocardial single-photon emission computed tomography images in the short-axis, vertical long-axis, and horizontal long-axis views revealed severe myocardial ischemia involving the anterior, septal, posteroinferior, and posterolateral planes of the heart. Coronary arteriography showed severe stenosis of the left anterior descending and right coronary arteries. The information from the exercise electrocardiogram (ECG), thallium-201 myocardial scintigraphy, and a coronary angiogram suggested that the false negative ECG response was due to ischemic ST-segment counterpoise (i.e., cancellation of ischemic ST-segment vectors, generated by equally extensive and severe ischemia involving myocardial planes opposite each other.

Electrocardiography↗

Ten years experience with therapeutic apheresis in a community hospital.

A retrospective study was carried out on 2,500 therapeutic hemapheresis procedures performed at a community teaching hospital from 1980 to 1990. Seventy-six percent of the procedures consisted of plasmapheresis (PE). The most frequently treated conditions were myasthenia gravis (MG), Guillain-Barré syndrome (GB), hyperviscosity (HV), and thrombotic thrombocytopenia purpura (TTP). Therapeutic results and clinical implications for these four conditions are discussed.

Adult↗

Identification of nematode larvae by coal cultures in closed boxes.

A method is described for the identification of concentrated larvae from coal cultures in closed boxes. The condensation drops formed beneath the lid of the culture box are taken up with an L-shaped pipette. The sample taken up is added to a drop of Lugol's solution on a slide and examined under the microscope. The details of the nematode structure are clearly visible. Great care should be taken to avoid a possible cutaneous contamination.

Animals↗