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Biomedical subjects

M Maille

Publications and source records attributed to M Maille.

At least 19 recordsLinked to original sources

[Multiple eccrine hydrocystomas of the eyelids in the framework of Schöpf syndrome. A case report].

Schöpf-Schultz-Passarge syndrome is a rare ectodermal dysplasia described by Schöpf in 1971. The disease is characterized by hypodontia, hypotrichosis, palmoplantar keratoderma, hypoplastic nails and eyelid hydrocystomas. We report the case of a 71-year-old man, the first French description of this syndrome, who remarkably presented all the signs. The patient also had skin tumors, multiple eccrime hidrocystomas and aspectific macular degeneration. A review of the literature is discussed.

Aged↗

[Pseudophakia and aptitude of aviation personnel].

UNLABELLED: Because of sensorial disruptions, aphakia post-cataract surgery is a cause of unfitness for the job of aeronautics flying personnel. Its correction thanks to intraocular lenses and a correct functional check-up permit to reconsider the fitness through a derogation given by the competent authorities. EQUIPMENT AND METHODS: The authors realized a retrospective study on the 5 last years. 27 flying personnel, 24 to 76 years old, went through a cataract surgery with implantation. The check-up includes a chemical exam completed by a morphoscopic, coloured and spatial study. RESULTS AND DISCUSSION: The files are more or less well-documented according to their origin. The flying personnel have an average of 4,010 flying hours. The average post-operative hindsight is 30 months. 3 wear intraocular lenses of rear chamber among which 1 is multifocal. 7 were examinated at the CPEMPN with satisfying morphoscopic, coloured and luminous sense compatible with the fitness. 4 are declared permanent unfit (1 professional pilot with bad results, 1 private pilot with other pathologies, 1 inexperienced stewardess getting through the admission visit with insufficient post-operative hindsight, 1 professional pilot declared unfit for its military activity in the reserve). 4 are qualified with restriction. 20 are qualified without restriction. CONCLUSION: The correction of aphakia with intraocular lenses permits in most cases to obtain good functional results compatible with the flying aptitude.

Adult↗

[Dacryocystography using CT and MRI. Comparative study apropos of 13 clinical cases].

Magnetic Resonance Imaging of a dacryocystography and a watersoluble computed tomographic dacryocystography were compared in 13 prospective cases after facial traumas, infections or without previous history. All had either watering eyes, ephiphora or dacryocystitis. This study demonstrated the superiority of computed tomography which must be used in first intention for complexe problems of the lacrimal drainage system. Only tumoral pathology (very rare) requires Magnetic Resonance Imaging. Combined computed tomography and dacryocystography in the same time provide diagnostic precision and less radiation. Confortable for the patient by helicoidal acquisition, computed tomography is cheaper than a Magnetic Resonance Imaging.

Adult↗

[Oculo-palpebral complication of vaccination. Review of the literature].

Post-vaccination eyes and eyelid complications are seldom seen. Clinically different, they are not only due to the small-pox vaccination which is no longer performed but may also be seen with various kinds of viral vaccines as well as bacterial vaccines except for polymyelitis and tetanus. We believe that vaccination contraindications, direction for use and propylactic treatment are useful.

Bacterial Vaccines↗

Dietary monounsaturated fatty acids enhance cholesterol efflux from human fibroblasts. Relation to fluidity, phospholipid fatty acid composition, overall composition, and size of HDL3.

This study was designed to determine whether modifications induced by dietary fats on the high-density lipoprotein3 (HDL3) physicochemical characteristics could affect cholesterol efflux and intracellular cholesterol content, leading to upregulation of low-density lipoprotein (LDL) receptor activity from cultured fibroblasts. Serum HDL3S were obtained from 12 healthy women aged 26 to 49 years who adhered to four 7-week isocaloric diets containing 30% of the caloric intake as fat. Of the total calories, 15.6% of each diet was provided by (1) milk fats, rich in saturated fatty acids; (2) sunflower oil, rich in n-6 polyunsaturated fatty acids; (3) olive oil, rich in monounsaturated fatty acids; and (4) rapeseed oil, rich in n-3 polyunsaturated fatty acids. HDL3 isolated after the monounsaturated fatty acid diet induced the greatest cellular [3H]free cholesterol efflux, reduced the content of intracellular cholesterol, and enhanced 125I-LDL degradation. Univariate regression analyses suggested that the increased capacity of HDL3 to promote cellular [3H]free cholesterol efflux was in part due to its greater fluidity, higher cholesteryl ester content, elevated linoleic to linolenic acid ratio in phospholipids, and its smaller size. In conclusion dietary fats induced physicochemical changes in HDL3, which strongly modulated cellular cholesterol homeostasis in vitro. These data also suggest a novel mechanism by which dietary fats exert their effect on atherosclerosis.

Adult↗

[Aids for low vision--strategic approach].

There are currently methods to rehabilitate the remaining visual function of visually impaired people. Treatment stages and tests are based on classical physiology of vision and still remain strictly experimental. Recent investigations showed that the visual system, as a whole, operates as a space frequency analyzer. There are reception to each spatial frequency. They have to be assessed with accuracy before any rehabilitation attempting to develop channels which are still functional by elective stimulation. This stimulation must have a maximum determined energetic efficiency. The study of the Fourier spectrum on two different images demonstrates this possibility and starts opening the way for specific research.

Contrast Sensitivity↗

A plasmid of Rhizobium meliloti 41 encodes catabolism of two compounds from root exudate of Calystegium sepium.

Our objectives were to identify substances produced by plant roots that might act as nutritional mediators of specific plant-bacterium relationships and to delineate the bacterial genes responsible for catabolizing these substances. We discovered new compounds, which we call calystegins, that have the characteristics of nutritional mediators. They were detected in only 3 of 105 species of higher plants examined: Calystegia sepium, Convolvulus arvensis (both of the Convolvulaceae family), and Atropa belladonna. Calystegins are abundant in organs in contact with the rhizosphere and are not found, or are observed only in small quantities, in aerial plant parts. Just as the synthesis of calystegins is infrequent in the plant kingdom, their catabolism is rare among rhizosphere bacteria that associate with plants and influence their growth. Of 42 such bacteria tested, only one (Rhizobium meliloti 41) was able to catabolize calystegins and use them as a sole source of carbon and nitrogen. The calystegin catabolism gene(s) (cac) in this strain is located on a self-transmissible plasmid (pRme41a), which is not essential to nitrogen-fixing symbiosis with legumes. We suggest that under natural conditions calystegins provide an exclusive carbon and nitrogen source to rhizosphere bacteria which are able to catabolize these compounds. Calystegins (and the corresponding microbial catabolic genes) might be used to analyze and possibly modify rhizosphere ecology.

Alkaloids↗

[Standard values for serum esterified fatty acids in adult women in good health].

Serum was obtained from two groups of 23 healthy female volunteers to determine the standard values of esterified fatty acids (EFA) contained in phospholipids, triglycerides and cholesterol. One group consumed an 'optimal' diet in regard to lipid and caloric content, under strictly controlled conditions, the other a free diet. All lipid fractions in serum from both groups were in the physiologic range so that the levels of EFA could be expected to be in the normal range. These data are comparable to those obtained from other series but they differ strongly from values established among the Eskimos, who have very low serum levels of arachidonic acid due to their traditional diet and probably to genetic factors. Determination of the standard values of EFA in healthy caucasian women may contribute to a better assessment of role of the therapeutic intervention on lipid parameters considered as atherogenic risk factors.

Adult↗

[Clinical value of the colored contrast sensitivity test. Preliminary note].

Evaluation of color contrast sensitivity is a new test for the assessment of visual capacity and especially of light stimulation transfer along the optic pathway. The color technique yields more accurate results. It is combined with previously existing functional examinations and allows very early detection of subclinical signs of starting pathological processes.

Color Perception Tests↗

[Trial of onager oil in the treatment of schizophrenia in connection with the prostaglandin deficiency hypothesis].

Ten schizophrenic patients were treated with onager oil. It was hypothesized that E1 prostaglandin deficiency underlies the different biological disorders of schizophrenia. The clinical and biological results were disappointing. However the fact that the patients had been severely ill for a long time might have to be taken into account. Moreover, the blood level of gamma-linolenic acid was normal, at the start, in all the patients.

Adult↗

A radiotechnique suitable for the detection of octopine synthesis in crown-gall tissues grown in vitro.

An improved method for the detection of octopine in Crown-gall tissues and in shoots regenerated from these tissues has been devised using [14C]arginine as a precursor. By using bidimensional chromatography followed by autoradiography, very small amounts of octopine can be clearly detected in tumors grown in vitro. Using this method, octopine was detected in tumor tissues when usual techniques were not sensitive enough.

Arginine↗

[Compensating presbyopia: a new physiological progressive lens (author's transl)].

After discussing the functional disadvantages arising after correction of presbyopia with uni--or multifocal lenses, the authors describe the optical and physiological advantages of a lens with progressively increasing power. The principal qualities of these physiologically progressive lenses are studies, and the results of a preliminary survey concerning their use are analysed. The indications for, and adaptation and tolerance of these lenses are outlined.

Aged↗