PubMed Health⌕ Search

Biomedical subjects

M Majak

Publications and source records attributed to M Majak.

14 recordsLinked to original sources
PubMed1994

Testicular histology after treatment with the new antiandrogen Casodex for carcinoma of the prostate. A preliminary report.

Five men aged 55-78 years, had received Casodex 50 mg p.o. daily for seven to 12 months. Because of tumour progression orchiectomy was performed. All testes were examined with light- and electronmicroscopy. Evidence of Leydig cell hyperplasia was present in testes from three patients. However, the ultrastructural appearance of the Leydig cells was normal. The spermatogenesis was reduced in all testes, although not significantly different from controls. We believe the Leydig cell hyperplasia reflects an increased proliferative stimulation by luteinizing hormone or a direct effect of Casodex.

Aged↗
PubMed1993

[Testicular trauma].

We report the cases of four patients with testicular injury following blunt scrotal trauma, and present a system of classification for testicular injuries. One patient had a rupture of tunica albuginea and three had intratesticular haematomas. Two patients were operated on with uneventful postoperative courses. Two patients with intratesticular injury were not explored. Both testes atrophied. We fear that many testes atrophy because of damage caused by pressure of intratesticular bleeding. Qualified surgical evaluation shortly after testicular injuries is of utmost importance for the prognosis.

Adult↗
PubMed1981

Morphological changes in the brains of female patients who died in connection with pregnancy or delivery.

The authors examined 23 brains of female patients who died during pregnancy or after delivery. Four clinical groups were distinguished: 1. sepsis, 2. gestosis, 3. patients with cardiac diseases, 4. other cases of death. General autopsy on all the dead patients was performed. Macroscopically the brain revealed the signs of oedema and herniationes. Microscopic findings showed in the sepsis and gestosis groups, distinct changes in small blood vessels. Their walls were often statified and impregnated with fibrin. In the cases with the DIC syndrome microthrombosis could be seen. Only in 2 patients cerebral arterial occlusion was noted. Neurons revealed the secondary changes described as anoxic encephalopathy.

Brain↗
PubMed1977

Ascites tumour NK/Ly as a model of the growth of malignant lymphoma in the brains of mice.

The NK/Ly ascites tumour inoculated into the brain of a mouse is well adapted and grows, causing clinical symptoms similar to a primary tumour of the brain. The clinical and histological features of the cerebral growth of the NK/Ly tumor (Nemeth-Kellner Lymphoma, 1960) are discribed. These features entitle us to treat NK/Ly tumour growth, transplated into the brains of mice as a model of malignant lymphoma in the C.N.S.

Animals↗