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Biomedical subjects

M Mandich

Publications and source records attributed to M Mandich.

4 recordsLinked to original sources
PubMed1999

Neonatal suck reflex pattern does not predict apnea.

Respiration and suck are gestational age-dependent reflexes modulated in the brain stem. To determine if the suck reflex pattern could be used to predict apnea, the relationship between the two was examined in 28 neonates. The suck reflex was quantified with respect to burst-pause rhythm, amplitude of negative suck pressure, and synchrony of the negative-positive pressure. Apneas were counted 5 days prior to and following measurement of the suck reflex pattern. Increasing gestational age correlated with a lower frequency of apnea (P < .01) and higher suck scores (P < .01). A mature suck reflex pattern, however, failed to predict the occurrence of apnea.

Apnea↗
PubMed1994

Motor development, infantile reactions and postural responses of preterm, at-risk infants.

Eighty-nine low-birthweight, preterm infants were enrolled in a longitudinal study to describe motor development, infantile reactions and postural responses during the first chronological year of life and to determine the relationship between these behaviors. There was a clear trend from prevalence of primitive patterns, such as the asymmetric tonic neck reflex, towards a prevalence of mature postural reactions such as the Landau, righting and protective extension reflexes. Statistical analysis suggested that a relationship exists between infantile patterns, automatic postural reactions and motor development that is similar to that accepted as normal in term infant development, when allowance is made for preterm birth. Correlations were also obtained between integration of the tonic labyrinthine response and the presence of the asymmetric tonic neck pattern at the time of hospital discharge and later achievement of motor milestones. These relationships warrant further investigation.

Female↗
PubMedDate not supplied

Assessment of motor development in very low birth weight infants.

OBJECTIVE: The purpose of the current investigation was to describe the fine- and gross-motor acquisitions of very low birth weight (VLBW) infants during their first 12 months without imposing traditional assessment assumptions. STUDY DESIGN: A nonrandomized, prospective study was used for a sample consisting of 89 VLBW infants whose motor development was assessed neonatally and at 4, 8, and 12 months chronological age. Fine- and gross-motor assessment items were selected and adapted from three standardized assessment instruments. RESULTS: The fine- and gross-motor systems of development appeared to be relatively independent of one another before the 8-month assessment. Thus, early fine-motor control appeared to develop almost to the exclusion of gross-motor progress. Once fine-motor control was established by 8 months, numerous gross-motor milestones followed and were present at 12 months chronological age. CONCLUSION: Current and previous data continue to define a developmental picture in which VLBW and fullterm infants achieve the same fine- and gross-motor milestones; however, the developmental pathways whereby milestones are achieved, during at least the first 12 months, appear to be different. Accordingly, applying instruments standardized on fullterm infants to the assessment of VLBW babies may not be serving us well on a number of different issues.

Aging↗