PubMed Health⌕ Search

Biomedical subjects

M Mantoni

Publications and source records attributed to M Mantoni.

At least 37 records · Page 2Linked to original sources
PubMed1990

Large intrauterine haematomata in threatened miscarriage. Frequency and clinical consequences.

Previously we described intrauterine haematomata seen with ultrasound in patients with threatened miscarriage and we suggested that a haematoma of greater than or equal to 50 ml might represent a risk to the pregnancy. We have now investigated 566 patients with vaginal bleeding in the first half of pregnancy and followed up 23 (4%) who had a haematoma of greater than or equal to 50 ml (mean 71 ml, range 50-150) at between 12 and 20 weeks gestation. One patient had a miscarriage and two had a preterm delivery, so that, contrary to our original suggestion, these large haematomata do not seem to represent any serious threat to the pregnancy.

Abortion, Threatened↗
PubMed1990

Function, morphology and protein expression of ageing skeletal muscle: a cross-sectional study of elderly men with different training backgrounds.

The function and morphology of knee extension/m. vastus lateralis and elbow flexion/m. biceps brachii were studied in young (28 +/- 0.1 years, n = 7) and elderly (68 +/- 0.5 years, n = 8) sedentary subjects and in elderly swimmers (69 +/- 1.9 years, n = 6), runners (70 +/- 0.7 years, n = 5) and strength-trained subjects (68 +/- 0.8 years, n = 7). On average, the training groups had, for the 12-17 years before the measurements were taken, performed their training regimen 3 +/- 0.1 times a week. Compared with the young subjects, the maximal isometric torque of the sedentary elderly subjects was 44% (P less than 0.05) lower in knee extension and 32% (P less than 0.05) lower in elbow flexion, and speed of movement was between 20 and 26% (P less than 0.05) lower in both knee extension and elbow flexion. The cross-sectional area of m. quadriceps femoris and the elbow flexors was also 24% (P less than 0.05) and 20% lower respectively, and the specific tension was 27% (P less than 0.05) lower in m. quadriceps femoris and 14% (P less than 0.05) lower in the elbow flexors. A 27% (P less than 0.05) higher content of myosin heavy chain type I and a 39% (P less than 0.05) higher content of the slow-type myosin light chain--2 was observed in m. vastus lateralis of the sedentary elderly subjects as compared with the young subjects. The same tendency was also seen with m. biceps brachii. Since the histochemical fibre-type distribution was identical and no major co-expression of type I and type II myosin heavy-chain isoforms was observed with immunocytochemistry, the increase in slow myosin isoforms with ageing seems mainly related to a larger relative area of type I fibres, induced by a selective atrophy of type II fibre area. An increased content of the beta-isoform of tropomyosin was also demonstrated with ageing. In contrast to the swimmers and runners, the elderly strength-trained subjects had maximal isometric torques, speed of movements, cross-sectional areas, specific tensions and a content of myosin and tropomyosin isoforms in both muscles studied identical to those of the young controls. These results seem to suggest that strength training can counteract the age-related changes in function and morphology of the ageing human skeletal muscle.

Aged↗
PubMed1990

Prevalence and significance of subchorionic hemorrhage in threatened abortion: a sonographic study.

We performed a prospective study to determine the prevalence and significance of subchorionic hematomas in patients with symptoms of threatened abortion. The study comprised 342 pregnant women who had vaginal bleeding in weeks 9-20 of pregnancy and a live fetus shown with sonography. Sonograms showed a subchorionic hematoma in 62 patients (18%). The average size of the hematoma was 20 ml (range, 2-150 ml). The rate of spontaneous abortion was the same in patients with and without hematoma, seven (11%) of 62 and 28 (10%) of 280, respectively. There was no association between abortion rate and hematoma size. The rate of premature delivery was the same in patients with and without hematoma, seven (11%) of 62 and 32 (11%) of 280, respectively. There was no association between the rate of premature delivery and hematoma size. Subchorionic hematomas are common and insignificant sonographic findings in patients with vaginal bleeding in weeks 9-20 of pregnancy.

Abortion, Threatened↗
PubMed1989

[Diagnosis of femoropopliteal venous thrombosis. Comparison of dynamic ultrasonic scanning and phlebography].

Forty patients with a clinical suspicion of deep venous thrombosis (DVT) of the lower limb were submitted to real-time ultrasound examination prior to venography. The ultrasound diagnosis DVT was made at the presence of at least one of two criteria: intraluminal thrombus and absence of vein compressibility. One ultrasound study was inconclusive. In 14 patients the ultrasound diagnosis was DVT, and in 12 of these this was confirmed at phlebography. There were thus two false positive ultrasonic diagnoses, PV pos = 0.86. In 25 patients, the diagnosis was no DVT on both ultrasound study and venography, PV neg = 1.00. Ultrasound examination is recommended as the first choice of diagnostic imaging in patients with suspected DVT.

Adult↗
PubMed1989

Intravenous digital subtraction angiography in patients with cerebral ischaemia. Evaluation of extracranial carotid lesions.

Over a two-year period, 167 patients with symptoms of transient ischaemic attacks or suspected minor stroke underwent intravenous digital subtraction angiography (DSA) of the carotid arteries. There were no major complications. Ninety-six patients had abnormal angiograms, 60 normal studies, and in 11 patients (7%) the examination was not of diagnostic quality, mostly because of motion artifacts. In 86 patients no therapeutic consequences resulted from the DSA examination. Twenty-six patients were referred for vascular surgery, and 34 patients had either anticoagulation or aspirin therapy. In 10 patients a primary medical cause was found for their cerebral vascular symptoms. It is concluded that intravenous DSA of the carotid arteries in patients with transient ischaemic attack is a safe, diagnostically useful procedure, that can also be used on an outpatient basis.

Adult↗
PubMed1985

Ultrasound signs in threatened abortion and their prognostic significance.

During the first and early second trimesters of pregnancy in 244 consecutive patients with uterine bleeding, ultrasound studies were conducted to determine the cause of bleeding. In 165 of the patients the fetus was alive, and the outcome of pregnancy was successful in 143 (87%) despite the fact that ultrasound scanning revealed a total of 60 abnormalities. In the 22 patients whose pregnancy outcome was unfavorable, the number of abnormalities was significantly higher (P less than .05). The most common ultrasound abnormalities were placenta covering the internal os, fetal growth delay, multiple gestation, and intrauterine hematoma. At ultrasound examination, the presence of one or more abnormalities plus bleeding for three days or more significantly increased the risk to the pregnancy. When the duration of bleeding was less than three days and the ultrasound examination was normal, the risk to the pregnancy was lower (7%) than that of patients who had bled for three days or more and had at least one abnormality on ultrasound examination (24%) (P less than .05).

Abortion, Threatened↗
PubMed1984

Obstetric ultrasonography: recent observations in first trimester of pregnancy.

It is possible both to accurately measure foetal size and visualize the yolk sac and the amniotic membrane by ultrasound scanning in the first trimester of pregnancy. In threatened abortion an intrauterine haematoma or a foetal size smaller than normal are ominous signs. Likewise, too small a foetal size in early diabetic pregnancy indicates an increased risk of foetal malformation.

Abortion, Threatened↗
PubMed1983

Ultrasound demonstration of the amniotic membrane.

Ultrasound scanning in the first trimester of pregnancy occasionally revealed a thin linear echo in the gestational sac. A total of 360 examinations, which had shown a live fetus with a crown-rump length of 7-82 mm, equivalent to a menstrual age of 6-14 weeks, were reviewed. The linear echo was seen in 51 of the examinations, at an ultrasound age of 6-12 weeks. Most frequently it was seen in the 9th week, where it was recorded in 28 of 61 (46%) of the examinations. The origin of the linear echo is believed to be the very thin amniotic membrane, which from the 8th to the 12th week is lined by fluid on both sides. Other intra-uterine membranes which all give stronger echo reflections are listed.

Extraembryonic Membranes↗
PubMed1982

Fetal growth delay in threatened abortion: an ultrasound study.

Out of 255 patients with threatened abortion 67 gave a regular menstrual history and at ultrasound examination had a live fetus with a crown-rump length (CRL) of 10-65 mm, equivalent to a gestational age of 7-13 weeks. The CRL of these fetuses was smaller than expected from their menstrual age (P less than 0.01). For this phenomenon we suggest the term early fetal growth delay. Seven patients aborted and one experienced intrauterine fetal death. These eight fetuses had on average smaller CRL than the remainder 59 fetuses (P less than 0.05). Fetal growth delay may therefore be considered a risk factor in threatened abortion.

Abortion, Threatened↗
PubMed1981

Intrauterine haematoma. An ultrasonic study of threatened abortion.

Ultrasonic scanning in patients with symptoms of threatened abortion occasionally revealed an echo-free area between the membranes and the uterine wall. The echo-free area was found in patients at 11 to 20 weeks gestation who had a live fetus and is believed to represent blood. Seven smaller haematomas of less than 35 ml gradually disappeared and the pregnancies continued until term. Three patients who had haematomas of more than 50 ml subsequently aborted or had a premature delivery.

Abortion, Threatened↗
PubMed1980

Threatened abortion studied by estradiol-17 beta in serum and ultrasound.

One hundred women were admitted to the hospital between 7 and 18 weeks' gestation because of vaginal bleeding and threatened abortion. Serum concentration of estradiol-17 beta was determined by radioimmunoassay. Ultrasound examination using a gray-scale scanner was performed as well. The values for prediction of abortion or successful outcome of pregnancy were calculated for estradiol (E2) and ultrasound separately and in combination. Prediction of abortion from a low E2 concentration combined with an ultrasound examination showing no fetal life was found to be totally reliable. Prediction of successful outcome of pregnancy from either a normal E2 or an ultrasound examination showing fetal life, or both, was 79.5% reliable. If no signs of fetal life were found by ultrasound examination from 10 weeks' gestation on, the pregnancy was doomed. Before this gestational age, measurements of E2 in serum gave supplementary information concerning the outcome of the threatened pregnancy.

Abortion, Threatened↗