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M Marrero Calvo

Publications and source records attributed to M Marrero Calvo.

7 recordsLinked to original sources
PubMed2001

[Chronic recurrent multifocal osteomyelitis].

Chronic recurrent multifocal osteomyelitis is a rare disorder of unknown etiology, characterized by multiple bone lesions and a variable clinical course. We present a 10 year old boy with chronic recurrent multifocal osteomyelitis who improved after treatment with naproxen.

Anti-Inflammatory Agents, Non-Steroidal↗
PubMed2001

[Acute osteomyelitis. Clinical, radiological and bacteriological features and outcome].

OBJECTIVE: To compare the clinical, radiological, bacteriological features and outcome of neonatal patients with acute osteomyelitis aged (28 days with those of children aged <= 28 days of age. PATIENTS AND METHODS: A retrospective analysis was performed. The clinical histories of patients aged less than 15 years diagnosed with acute osteomyelitis in a tertiary care hospital were reviewed. Acute osteomyelitis was defined as the association between at least two of the following variables: a) positive blood or biopsy culture; b) purulent bone aspiration; c) clinical features compatible with a diagnosis of acute osteomyelitis; d) radiological features suggestive of acute osteomyelitis, and e) favorable outcome after antibiotic treatment. The patients were divided into two groups: group 1: neonatal patients (aged (28 days) and group 2: children aged <= 28 days. Statistical analysis was performed by the Chi-square test and Student's t-test for categorized and numeric variables, respectively. RESULTS: Between 1977 and 1999, 45 children aged less than 15 years old were diagnosed with acute osteomyelitis. Of these, 17 patients were neonates (group 1) and 28 patients were aged more than 28 days old (group 2). The male:female ratio was 1.1:1 in group 1 and 3:1 in group 2. The mean age was 17.7 +/- 7.5 days in group 1 and 7.2 +/- 4.3 years in group 2. Metaphysis and tibia were more commonly affected in group 2 (p < 0.05). Epiphysis, arthritis and humerus were more frequently affected in group 1 (p < 0.05). Osteolysis and periosteal reaction predominated in group 1 (p < 0.05). 99mTc Bone scintigraphy and magnetic resonance imaging showed pathological findings in all patients. Blood culture revealed Staphylococcus aureus in 46 % of the patients. Blood and biopsy material cultures were positive in 46 % and 75 %, respectively. Of the 45 patients, outcome was favorable in 37 (82.2 %). CONCLUSION: Acute osteomyelitis showed different characteristics in the neonatal and postnatal periods. Bone scintigraphy and magnetic resonance showed high sensitivity. Bacteriology was positive in 50 % of patients.

Acute Disease↗
PubMed1998

[Neonatal sepsis caused by Streptococcus agalactiae. What should be done?].

OBJECTIVE: Within the common pathogenic flora responsible for neonatal sepsis, streptococci group B (SGB) is the most frequently found etiological agent. The fact that it is a frequent colonizer of the female perigenital area has resulted in a whole host of detection and eradication strategies via preventative measures applied to the pregnant woman to eliminate vertical transmission to the newborn. PATIENTS AND METHODS: We present a revision of SGB sepsis and our protocol based on the intrapartum treatment of those pregnant women with risk factors and the study in the newborn at risk of infection with early detection of particles of Latex in urine for SGB (Slidex Strepto B bioMerieux), as well as the customary analytical and bacteriological tests. We have also revised the different strategies in medical scientific publications and several neonatal units for the management of this infection and compare this with our protocol. RESULTS: During the period 1986-1996 the incidence of SGB sepsis was 0.9/1,000 (19 cases), with an incidence of neonatal sepsis of 4.08/1,000. The incidence of sepsis caused by Streptococcus agalactiae in our environment is low, although it has increased from 15.9% to 28% comparing the first five years with the following six years, with a fatality rate of 10.5%. We believe that the most effective strategy for this problem is intrapartum identification and treatment of the pregnant woman at risk and early diagnosis of the newborn resulting from this pregnancy. CONCLUSIONS: We based our strategy on two vias, intrapartum treatment of mothers included in the high risk infection group and in the neonatal unit by early routine detection of SGB in urine. We have obtained a low incidence rate, low mortality rate and avoid false negatives of carrier mothers.

Ampicillin↗