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Biomedical subjects

M Martínez-Albaladejo

Publications and source records attributed to M Martínez-Albaladejo.

16 recordsLinked to original sources
PubMed1998

[T-gamma lymphocytosis associated with two solid neoplasms in a patient with rheumatoid arthritis].

T gamma lymphocytosis is an infrequent entity, generally benign and distinct of the spectrum of the T cell chronic lymphoproliferative syndromes, that it not need or need short therapy, with a prolongated survival. T gamma lymphocytosis is expressive in the most of the occasions of a monoclonal lymphocytic proliferation and it is frequently associated to Rheumatoid Arthritis. We present the case of a patient with T gamma lymphocytosis, developed after several years of evolution of Rheumatoid Arthritis and that it was coincident with two solid neoplasms, an infiltrate carcinoma of the larynx and recurrent urothelial carcinoma, without previous chemotherapy. The death in this patients, is generally due a progressive lymphoproliferation and sepsis relationed with the neutropenia.

Aged↗
PubMed1995

[Amyloid intestinal pseudo-obstruction as initial manifestation of IgA multiple myeloma].

Amyloidosis is a well known complication of Multiple Myeloma. Although involvement of the gastrointestinal tract is common in patients with Amyloid, severe symptoms are no frequent, nevertheless vascular deposits may produce gastrointestinal ischemia and bleeding and perforation. Injured mucosae of the intestinal well may produce malabsorption and the neuromuscular infiltration determine alterations of gastrointestinal motility. Although renal and cardiac disfunction is the most frequently cause of death in these patients, intestinal pseudo-obstruction bears a serious prognosis. We present a case of a patients who was operated because of a presumptive diagnosis of intestinal obstruction, which small bowel was infiltrated with Amyloid and which bone marrow demonstrated multiple myeloma.

Amyloidosis↗
PubMed1995

[Delayed intestinal obstruction due to a seatbelt].

During blunt abdominal trauma the small bowel and/or its mesentery may be injured; if abdominal trauma occurs after compression by an incorrectly-applied seat belt, underlying viscera may be crushed between the vertebral and the seat belt; ischemia or infarction of the intestinal wall, and delayed fibrosis and stenosis may occur. We present a patient, operated on two months after blunt abdominal trauma, with small bowel obstruction secondary to post-traumatic intestinal fibrosis. Assuming that this condition is rarely suspected, a delayed diagnosis and treatment of these patients may occur.

Abdominal Injuries↗
PubMed1995

[With respect to Tinel and Phalen's signs].

The increment sensibility of the median nerve's compressed fibres in the carpal tunnel constitute the basis of the most known clinical tests, Phalen's test an Tinel's sign, used for diagnosis of the Carpal Tunnel syndrome. The frequence of these signs found in the literature is very variable, by this reason we realized this work, for determining the correlation between these tests and the clinical features and the electro-diagnosis. In our series (288 hands) the Tinel's sign demonstrate significative correlation with the motor and sensory conduction velocity (p < 0.05), showing significative increase of its frequence when distal motor and sensory latency were upper 4.5 ms. Phalen's test non correlated with any electrical parameters. Nevertheless, 97% of cases with positive Phalen's test were typical clinic forms of Carpal Tunnel syndrome, white 85% of cases with positive Tinel's sign concerned to typical group.

Adult↗
PubMed1993

[Carpal tunnel syndrome II. Clinico-electroneurological correlation].

In patients with carpal tunnel syndrome (CTS), it has frequently been observed a disparity between the clinical manifestations, especially pain, and the electroneurological (ENG) tests, the reason for which we have conducted this study, in order to assess to what extent the symptoms and signs of CTS are correlated with the ENG findings. The study included 288 hands, 190 patients with ENG diagnosis of CTS, 127 of which were women and 63 men. With respect to the sensitive manifestations observed, pain was present in 146 hands (50.87%), paresthesia in 142 hands (49.47%) and objective hypoesthesia in 43 hands (14.98). All these manifestations were significantly correlated with sustained sensitive distal latency (SDL). In addition, hypoesthesia was correlated with reduced sensitive conduction rate (SCR). Among the motor manifestations, the subjective loss of strength was referred in 102 hands (35.54%), the objective loss of strength we observed in 49 hands (17.07%) and atrophy in 22 hands (7.66%). We observed a significant correlation between objective motor signs, mainly atrophy, and altered electroneurological motor parameters; there was also a significant correlation between the time of evolution of the process and the presence of thenar atrophy. As well as with the sensitive clinical manifestations, the objective physical findings correlated more significantly with the electroneurological findings than with the subjective manifestations.

Atrophy↗
PubMed1993

[Carpal tunnel syndrome I. Clinico-epidemiologic study].

As part of a greater study, we conducted this work in which we evaluated the epidemiologic, etiopathogenic and clinical aspects of a series of 190 patients (288 pathological hands) diagnosed of carpal tunnel syndrome (CTS) with electroneurological procedures (ENG). Sixty-six point eighth per cent were women and 33.1% men, with an initial average age of 44.8 years for men and 43 years for women (NS difference). The average time of evolution of symptoms was 1.38 years for men and 2.4 for women (p < 0.01). Etiological or predisposing factors were observed in 17.3% of patients and systemic factors in 44.6%. Fifty-eight per cent of men performed hard manual activities, whereas 75.4% of women performed non-professional domestic tasks. The symptomatology was non-specific in 15.6% of the patients, whereas 18% of the patients were asymptomatic, although their ENG was compatible with CTS. Among the major clinical manifestations were pain (50.8%) ad parenthesias (49.4%), with less frequent observation of strength loss (17%), hyposthesia (15%) and thenar atrophy (7.6%). We support most of the data brought forward by previous literature, female predominance and maximum incidence in middle ages. We observed as the most frequent cause work activities entailing reiterative and sustained movements of the wrist and we did not find any other sign or symptom totally reliable for the diagnosis of CTS, being the bioelectrical tests the ones with less errors.

Adolescent↗
PubMed1992

[Q fever and endocarditis. Apropos a new case].

Endocarditis is the first manifestation of Q fever in its chronic form, generally affecting prosthetic cardiac valves or previously injured valves. Its clinical presentation is an endocarditis with negative culture and there is not agreement with regard to the most adequate antimicrobial treatment and its duration. Frequently, the valve has to be replaced. We present a case of a patient with double aortic lesion, in whom endocarditis by Q fever was diagnosed and treated with doxycycline, initially with success. However, she relapsed one year later, being then resistant to the medical treatment (doxycycline, ciprofloxacine plus rifampicine). It was not possible to replace the valve and the patient died two months later due to cardiac failure.

Aged↗