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M Mattioli

Publications and source records attributed to M Mattioli.

96 records · Page 6Linked to original sources
PubMedDate not supplied

[Magnetic resonance angiography in liver transplant patients. Follow-up of vascular anastomoses].

Twenty liver transplant patients were examined with MRA and color-Doppler US 18 to 40 days after surgery to investigate the onset of vascular complications after surgical liver revascularization. Vascular anastomoses are the most frequent location for such complications as stenoses, occlusions, pseudoaneurysms and vessel ruptures. In liver transplant there are 4 vascular anastomoses, i.e. hepatic artery, portal vein and superior and inferior anastomoses of the inferior vena cava. MRA images were acquired with a superconductive unit operating at 1.5 T, using fast low angle shot (FLASH) 2D sequences on the coronal plane; all images were postprocessed with the MIP algorithm. The presence of a paramagnetic artifact, the "double black spot sign", caused by the suture wire used to make the vascular anastomoses, allowed us to precisely detect the site and the flow pattern alterations at this level. MRA images were studied by two independent observers and vascular anastomosis depiction was rated as "good", "fair" and "poor". The demonstration of portal vein anastomoses was good in the whole series (20/20 patients). The superior anastomosis of the inferior vena cava was clearly depicted in 19 cases and fairly depicted in only 1 patient. The inferior anastomosis of the inferior vena cava was clearly depicted in 19 patients and fairly depicted in 1 case. Hepatic artery anastomoses were far more difficult to demonstrate than the others, considering their caliber and flow pattern, but its depiction was nevertheless good in 12 cases, fair in 6 and poor in only 2 patients. In our series, only one portal vein stenosis was observed, which was clearly depicted on both MRA and US images. In conclusion, MRA is a useful and reliable noninvasive diagnostic tool to study vascular anastomoses in liver transplant patients.

Adolescent↗
PubMedDate not supplied

[Treatment results in pT2, NO1 breast cancer. )A retrospective analysis of 85 cases)].

The authors report on 85 T2 breast carcinoma treated from March 1984 to February 1991. The median age was 55.7 years (range: 24-82). The most common type of tumor was infiltrating ductal carcinoma (88.2%). T pathological diameter was in 69 cases < or = 3 cm (81.2%). 47 patients showed pathologically positive axillary nodes (55.3%). Radical mastectomy with total axillary dissection, preferably modified by Patey or Madden (78.8%), was the treatment of choice. Only 5 patients were submitted to conservative surgery (quadrantectomy plus radiotherapy). Mean follow-up time was 42 months. For all considered patients, crude and without evident disease 3 and 5 years actuarial survival was evaluated. Distant metastases were observed in a total of 12/85 patients (14.1%), mainly in N+ with more than 3 nodes (31.5%) three times associated to loco-regional failures. Results at June 1992, as occurrence of first failure from the date of surgery are described. Different therapeutic managements are discussed. Prognosis of T2 breast carcinoma remains still poor. Limited surgery in association with radiotherapy and/or pre- and postoperative chemotherapy in N+ patients with more than 3 nodes or N- patients with high cell proliferation index, seems to be encouraging to T2 cases with a diameter less than 3 cm, when local conditions are suitable for good final aesthetic results.

Adult↗
PubMedDate not supplied

[Late radiation-induced injuries: breast carcinoma in post-actinic ulceration of the thoracic-breast region with infected osteoradionecrosis. A case report].

Severe skin reactions are commonly observed after breast irradiation. Chronic ulcerations, soft tissue damage and osteonecrosis are well-known though relatively rare long-term radiation-induced injuries. The ever-present possibility of recurrence or persistence of the primary malignant neoplasm within the irradiated tissue must be always suspected and adequately established by multiple biopsies before planning an eventual resective and or reconstructive strategy. In the present report a neoplastic recurrence arised from an extensive radiation-induced ulceration along the parasternal area with chest wall osteonecrosis complicated by infection in a 42 y.o. woman, who had received postoperative roentgen therapy a long time before for breast carcinoma and thyroid cancer, is described. Radiation-induced injuries and therapeutical options are discussed in relation to the site of the lesion and to the complexity of the single case. In conclusion, when recurrent malignancy is present, although the long-term prognosis may be poor, the quality of life of many patients undoubtedly may be improved by a multidisciplinary approach involving oncologysts, as well as general, thoracic and plastic surgeons.

Adenocarcinoma, Papillary↗