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Biomedical subjects

M Mazor

Publications and source records attributed to M Mazor.

At least 127 records · Page 7Linked to original sources
PubMed1986

Complications associated with the macrosomic fetus.

A retrospective study was done on 525 infants who weighed more than 4,500 g. The rates of grand multiparity, diabetes mellitus, pregnancy-induced hypertension, deliveries in women over 35 years of age, placenta previa and weight gain of more than 15 kg were higher than in a control group weighing 2,500-4,000 g. The rates of delivery with instruments and cesarean section were also significantly higher. The main indication for cesarean section in the study group was cephalopelvic disproportion, while in the control group it was repeat cesarean section. Rates of postpartum hemorrhage, shoulder dystocia, oxytocin augmentation of labor and tears in the birth canal far exceeded those in the control group. Maternal and fetal morbidity and perinatal mortality were significantly higher than in the control group. The complications were due to a difficult second stage of labor. Delivery of the macrosomic fetus by cesarean section is highly recommended except for the subgroup of women who already delivered a macrosomic child.

Adult↗
PubMed1986

Management and outcome of multiple pregnancies complicated by the antenatal death of one fetus.

Over a 15-year period, infants from 1,192 multiple gestations were delivered at Soroka Medical Center, Beer Sheva, Israel. In 21 patients the pregnancy was complicated by the antenatal death of one fetus. In 2 of the 4 cases of monochorionic placenta, both twins died in utero within a short time, while in the 17 cases of dichorionic placenta there was no second fetal death. It seems that in cases of monochorionic placenta, the surviving twin is exposed to a more dangerous environment, and death can occur imminently. The management protocol should be based, if possible, on the type of placentation.

Adult↗
PubMed1986

[Restoration of fertility following excision of an intracranial hydatid cyst].

An unusual case of a 31 year-old Bedouin women, with secondary infertility of 13 years' duration who conceived twice spontaneously after removal of a hydatic cyst from her frontal lobe is reported. The reproductive function was restored probably by releasing the hypothalamic-pituitary axis from the pressure exerted by the cyst.

Adult↗
PubMed1986

[Intrauterine death of one of the fetuses in a twin pregnancy].

A case of twin pregnancy complicated by intra-uterine death of one fetus 10 weeks before term is described. The occurrence of this complication raises difficult questions about the management and outcome of this rare event. A review of 23 patients with similar findings brought us to the conclusion that the management protocol to be applied should be based, if possible, on the type of placentation.

Adult↗
PubMed1985

Absence of fetal movements and normal infants.

Pregnant women feel movements from about the fifth month of pregnancy. In cases of high-risk pregnancy daily recording of fetal movements is useful in monitoring fetal well-being. Complete cessation of fetal movements points to a severely distressed fetus and impending death. We report here five women in whom failure to experience fetal movements was present from the beginning of pregnancy, or occurred after fetal movements had been felt for several weeks during the pregnancy. All the women delivered normal infants with high Apgar score.

Adolescent↗
PubMed1985

The ultrasound score and fetal heart-rate pattern as predictor of fetal outcome.

Over a period of one year 312 high-risk patients (HRP) were prospectively monitored using ultrasound score (USS), nonstress test (NST) and contraction stress test (CST). There were nine cases with low USS, seven of them had reactive NSTs, were delivered vaginally without any evidence of distress in labour and had normal Apgar scores with no perinatal morbidity. In the remaining two cases the NST was nonreactive and they were delivered by cesarean section because of fetal distress. The NST was not reactive in 18 patients, eight of them subsequently had abnormal CST and displayed fetal distress during labour. The USS was high in 16 cases. The results of this study seems to indicate that in cases with nonreactive NST, CST is a better predictor of fetal outcome than the ultrasound score.

Female↗
PubMed1985

Fetal malformations associated with breech delivery. Implications for obstetric management.

Among 1,411 breech deliveries at the Soroka Medical Center, Beer-Sheva, Israel, there were 116 cases of congenital anomalies (8.2 %). Forty-nine fetuses (3.47%) exhibited major congenital anomalies and 67 (4.7%), minor ones. The incidence of chromosomal anomalies was 0.63% (1 per 159 births) as compared with 0.25% in the general population. The frequency distribution indicated that most of the fetuses with congenital abnormalities weighed 2,000 gm or more. In view of the high incidence of chromosomal aberrations and major congenital anomalies among fetuses with breech presentation, it seems desirable to consider ultrasonographic assessment and chromosomal analysis during the last trimester of pregnancy.

Adult↗
PubMed1985

[Necrotizing fasciitis following abdominal hysterectomy].

Necrotizing fasciitis is a rare disease with a high mortality and morbidity rate. The authors report the case of a 52 year old woman with necrotizing fasciitis following abdominal hysterectomy. The early diagnosis and the radical surgery saved her life from this serious type of infection. By describing this case, the authors wish to emphasize their opinion that early diagnosis is essential to survival and the most important aspect of management is early aggressive surgical intervention.

Fasciitis↗
PubMed1984

Ethical dilemma of late pregnancy termination in cases of gross fetal malformations.

Modern diagnostic methods reveal an increased number of cases of gross fetal malformations, and physicians are faced with serious ethical considerations. The disclosure of data during conversations with the parents, the decision-making process and the different courses of action are discussed. Cases with defined diagnoses may be divided into three different clinical situations: 1) a malformation incompatible with extrauterine life; 2) increasing organ damage caused by a fetal defect; and 3) a severely handicapped fetus capable of short- or long-term survival. The recent concept of fetal abuse is emphasized. When pregnancy is allowed to continue to term in these cases, psychological and social aspects must be taken into consideration. Medical assessment, ethicolegal norms, and religious beliefs of parents and physicians should guide the course of action. We believe that the medical team should perform late termination of pregnancy when justified and approved by a court or a statutory committee.

Abnormalities, Multiple↗
PubMed1983

The significance of single sporadic deceleration during a nonstress test.

The significance of single sporadic deceleration occurring during antepartum fetal heart rate monitoring was assessed. Single sporadic deceleration was defined as a drop of fetal heart rate of at least 40 bpm below baseline lasting for at least 2 min. During the year 1980, 7202 nonstress tests (NST) were performed in pregnant patients, with gestational ages ranging from 32-42 wk. Among these, 62 cases of single sporadic deceleration were observed. In 48 of these cases the single sporadic deceleration was followed by a normal reactive NST. In 14 patients NST following the single sporadic deceleration was non-reactive. In those cases oxytocin challenge test (OCT) was performed and was negative in 10 and positive in 4 cases. In the latter 4 patients labor was induced and all required cesarean section because of severe fetal distress. The remaining 58 women were followed up at the High-Risk Pregnancy Unit until spontaneous labor began, their deliveries were monitored throughout. In 8 cases out of the 58, fetal distress was observed during labor and in 4 of them cesarean section was required. The occurrence of single sporadic deceleration at gestational ages 32-42 wk is not an alarming sign providing the NST and/or O.C.T. are normal. However, the incidence of fetal distress during labor is significantly higher in fetuses with single sporadic deceleration as compared to the normal parturient population.

Female↗
PubMed1982

Effect of cannabinoids on the activity of monoamine oxidase in normal human platelets.

Platelet MAO activity was affected by preincubation with cannabinoid derivatives in vitro. The psycho-active derivative delta 1-THC inhibited MAO activity in platelets to an extent varying according to its concentration while CBD and (+) delta 6-THC had no inhibitory effect. (-) delta 6-THC, which is minor psychomimetic component, had less inhibitory effect on MAO activity than delta 1-THC. However, (-) DMH delta 6-THC revealed no attenuation effect on MAO inspite of its well-known psychomimetic activity.

Adolescent↗
PubMed1981

Primary carcinoma of the cecum with uterine metastases.

We report an unusual case of a poorly differentiated signet ring cell type of adenocarcinoma of the cecum, rare in its own right, that had metastasized to the endometrium. The diagnosis was made on the basis of fractional uterine curettage. It is believed that this is the first case of such an unusual cecal carcinoma metastatic to the endometrium.

Adenocarcinoma↗