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Biomedical subjects

M McCann

Publications and source records attributed to M McCann.

33 records · Page 2Linked to original sources
PubMed1990

Acute haemodialysis during the Armenian earthquake disaster.

On the 7 December 1988 an earthquake struck a densely populated region in northern Armenia. Up to 50,000 people were killed and many thousands were seriously injured. At least 385 of these casualties developed acute renal failure secondary to crush syndrome and required dialysis. The Armenian renal unit at Yerevan, in common with units elsewhere, was already overstretched to cope with the dialysis requirements of their patients with chronic renal failure before the earthquake. Most of the patients requiring dialysis were transferred to other hospitals in the USSR but 120 patients remained in Yerevan, the majority at the regional renal unit, overwhelming the resources. We assisted by taking a team of dialysis personnel, equipped with portable haemodialysis machines, to Yerevan. We performed 57 haemodialysis sessions and treated 15 patients, 13 of whom ultimately survived. Valuable lessons were learnt about the medical management of disasters abroad.

Acute Kidney Injury↗
PubMed1990

Cell surface phenotype, cytokines, and antibody gene expression in immortalized human B cell lines.

In an attempt to gain some insight into the many factors influencing antibody gene expression in human B cell lines, we have examined in detail the relationship between cell surface phenotype, cytokines, and the growth and antibody-producing capacity of a panel of immortalized human B cell lines. The cell panel comprised lines secreting either high or low titers of antibodies against Rhesus D, hepatitis B surface, and tetanus toxoid antigens. All the transformed cell lines exhibited a cell surface phenotype characteristic of well-differentiated peripheral blood cells strongly expressing CD23 and CD38 while weakly expressing CD10 and CD21. There was no obvious relationship between the antibody-body-secreting and proliferative capacity of the cell lines and their cell surface phenotype. Antibody secretion by the cells was rarely improved by the addition of a wide range of doses of recombinant IL-2, IL-4, or IL-6. In addition, such treatment frequently inhibited proliferation. Supernatants from some of the cell lines promoted the growth of unrelated cell lines but failed to influence antibody production. Such supernatants contained the highest concentration of IL-1, TNF beta, TGF beta, and soluble CD23. In contrast, the heterohybrid supernatant which inhibited cell growth secreted low levels of these cytokines. None of the cell lines secreted detectable amounts of IL-2, IL-4, INF gamma, or GCSF. There was no obvious relationship between cytokine production and antibody secretion. Finally, LPS had a slight but variable effect on antibody secretion but failed to influence cell growth.

Antibody Formation↗
PubMedDate not supplied

The European Post-Basic Core Curriculum (PBCC) 2nd Edition for Nephrology Nursing: Progress Update.

It is ten years since the publication of the first edition of the Post-Basic Core Curriculum (PBCC) and following a review of this edition, by the Education Board of the EDTNA/ERCA, a second edition of the PBCC was published in 2004. This edition is currently available as a hard copy and on CD-ROM. The second edition includes changes to the structure and content of the curriculum, which reflects contemporary developments in Renal Care and Nephrology Nursing.

Accreditation↗
PubMedDate not supplied

Health and safety programs for art and theater schools.

A wide variety of health and safety hazards exist in schools and colleges of art and theater due to a lack of formal health and safety programs and a failure to include health and safety concerns during planning of new facilities and renovation of existing facilities. This chapter discusses the elements of a health and safety program as well as safety-related structural and equipment needs that should be in the plans for any school of art or theater. These elements include curriculum content, ventilation, storage, housekeeping, waste management, fire and explosion prevention, machine and tool safety, electrical safety, noise, heat stress, and life safety and emergency procedures and equipment. Ideally, these elements should be incorporated into the plans for any new facilities, but ongoing programs can also benefit from a review of existing health and safety programs.

Art↗
PubMedDate not supplied

Mortality patterns among professional artists: a preliminary report.

Causes of death among 1598 professional artists were compared with an expected distribution based on the general U.S. population to determine if there were unusual patterns of fatal disease that might be indicative of exposure to hazardous substances in their work environment. Deaths among men and women in the arts were identified from obituaries in Who's Who in American Art published between 1940 and 1969. Among 1253 white male artists, PMRs were significantly elevated for arteriosclerotic heart disease, leukemia and cancers of the bladder, colon, rectum, kidney, and brain. The significant excesses of bladder cancer and leukemia deaths were limited to painters. Proportions of deaths due to colon cancer were significantly elevated among male painters and sculptors. Prostate cancer mortality was slightly higher than expected among painters and significantly elevated among sculptors. Among 345 female artists, painters represented the only specialty category large enough to analyze and excess numbers of deaths due to cancers of the rectum, lung, and breast were noted.

Aged↗