Polyoptimum--a review.
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Biomedical subjects
Publications and source records attributed to M McKinnon.
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Midline cervical cleft is a rare congenital anomaly of the ventral neck. A series of 12 cases of midline cervical clefts over a 30-year period is reported. This anomaly is part of a spectrum of midline branchiogenic syndromes resulting from abnormal migration of cells derived from the branchial arches. The preferred operative correction requires complete excision of the cleft with its underlying fibrous cord and closure with multiple Z-plasties.
A survey of peptic ulcer disease in Western Samoa is described. As compared with New Zealand experience, an unusually high prevalence of peptic ulceration is documented. A remarkable and significant variation in the geographic distribution of cases is reported. Regions of high prevalence were significantly associated with disease onset at an earlier age and with increased frequency of a family history of ulcer disease. It is concluded that this genetic predisposition is unlikely to sufficiently account for the regional localisation of cases observed and environmental causes are under study.