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M Mehra

Publications and source records attributed to M Mehra.

46 records · Page 3Linked to original sources

Difficult cases in heart failure: Expanding the therapeutic armamentarium in decompensated heart failure: using intravenous fenoldopam.

The authors report the clinical use of fenoldopam, a dopamine agonist, in a patient with decompensated heart failure and severe pulmonary hypertension. In addition, they explore the potential mechanisms by which fenoldopam exerts its beneficial effects and review the literature regarding the use of this agent in systolic heart failure. (c)2001 by CHF, Inc.

Journal Article↗

Enzyme changes in the brain, liver and kidney following repeated administration of mercuric chloride.

Alterations in the levels of selected enzymes have been studied in the liver, kidney and brain of mouse following mercuric chloride (1 mg/Kg body wt./d) administration for 10, 20 and 30 d. The activity of acid phosphatase increased in all the tissues, the highest increase was recorded in the kidneys which showed as much as 4.5 fold elevation following mercuric chloride administration for 30 d. Although the alkaline phosphatase activity in the liver and the brain increased following HgCl2 administration, the kidneys experienced a tremendous decline in this enzyme following the same treatment. Mercury-induced changes in ATPase were complex inasmuch as the nature and magnitude of these changes varied with the tissue as well as the duration of the treatment. Whereas the liver ATPase declined after all the treatment intervals, this enzyme increased in the kidney and brain following administration of HgCl2 for 10 d. However, both the kidneys and brain registered a substantial fall in ATPase activity when HgCl2 administration was continued for 30 d. The levels of both glucose-6-phosphatase and succinic dehydrogenase decreased in all the tissues following HgCl2 administration. Invariably, the magnitude of decrease was the highest after 30 d treatment with HgCl2.

Acid Phosphatase↗

Child health.

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Child↗